Results 71 to 80 of about 426,940 (310)

Antibiotics for cancer therapy

Oncotarget, 2015
Elegant studies by Lisanti, Sotgia and co-workers demonstrate that when breast cancer cells are grown under conditions that promote 3D-sphere formation, which selects for cancer stem cells, that mitochondrial proteins are dramatically induced. Importantly, these studies also show that antibiotic agents that function as mammalian inhibitors of ...
Pestell, Richard, Rizvanov, Albert A
openaire   +2 more sources

Antibiotic Resistance in Nosocomial Bacteria Isolated from Infected Wounds of Hospitalized Patients in Czech Republic

, 2020
Hospitalized patients with wounds face an increased risk of infection with multi-drug-resistant nosocomial bacteria. In this study, samples from almost 10,000 patients from big hospitals in Czech Republic with infected wounds were analyzed for the ...
Milan Kolar, Lenka Hobzova, Pavel Bostik, Katerina Neradova, Patrik Mlynarcik, Katerina Bogdanova, Pavel Cermak   +6 more
core   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

Antibiotic Therapy

Deutsches Ärzteblatt international, 2021
Peter, Becker, Dieter, Schilling
openaire   +3 more sources

Evaluation of the Use of Preventive Antibiotic Therapy in Patients Undergoing One-Step Prosthetic Revision Surgery with Low Preoperative Infectious Risk

Introduction: The prosthetic knee infection (PKI) rate in most centers ranges from 0.5 to 2% for knee replacements, depending on risk factors. Current PKI definitions may miss the identification of both early and late complications. There is no consensus
Stefania Marocco, Giacomo Stroffolini, Lorenzo Povegliano, Leonardo Motta, Giulia Bertoli, Claudio Zorzi, Gianluca Piovan, Federico Gobbi   +7 more
core   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Ambulatory Intravenous Antibiotic Therapy in Quebec: The Hôpital Charles LeMoyne Experience in 1996

Canadian Journal of Infectious Diseases, 2000
From January 1, 1996 to December 31, 1996, 343 patients received outpatient intravenous antibiotic therapy at Charles LeMoyne Hospital, a 436-bed, acute care hospital in Greenfield Park, south of Montréal, Québec. The infectious diseases department saved
Laurent Delorme, Charles Frenette, Isabelle Le Corre, Julie Duchesne, Carole Delorme, Pauline Plourde   +5 more
doaj   +1 more source

Is fixed short-course antimicrobial therapy justified for patients who are critically ill with intra-abdominal infections?

Journal of the Anus, Rectum and Colon, 2019
A long-course antibiotic therapy increases the risk of antibiotic resistance. A 7- to 14-day duration of therapy has been traditionally adopted in patients with intra-abdominal infections (IAIs).
Yoshio Takesue, Motoi Uchino, Hiroki Ikeuchi, Takashi Ueda, Kazuhiko Nakajima   +4 more
doaj   +1 more source

pFAR plasmids: New Eukaryotic Expression Vectors for Gene Therapy, devoid of Antibiotic Resistance Markers

, 2008
Efficient production of eukaryotic expression vectors requires the selection of plasmid-containing bacteria. To avoid the risk of dissemination of antibiotic resistance markers, we developed a new system to produce a family of plasmids Free of Antibiotic
Corinne Marie, Daniel Scherman, Veronique Preat, Gaelle Vandermeulen, Mickael Quiviger, Magali Richard   +5 more
core  

Antimicrobial Lock Therapy: A Strategy for Managing Catheter-Related Bacteremia

Objectives: This study aims to evaluate the use and efficacy of antibiotic-lock therapy (ALT) in the management of catheter-related bloodstream infections (CRBSIs), focusing on its impact on infection resolution, catheter retention, and clinical outcomes.
Firdevs Aksoy, Hanife Nur Karakoc Parlayan, Gulter Oncu Kurutas, Gurdal Yilmaz   +3 more
core   +1 more source