Results 1 to 10 of about 7,256 (181)

Thoracoscopic crush biopsy unmasking drug resistant extrapulmonary tuberculosis [PDF]

IDCases
Tuberculosis remains a major global health concern with extrapulmonary manifestations contributing to approximately 15–20% of cases in immune-competent hosts. In 2022, National Tuberculosis Elimination Program (NTEP) reported multidrug resistance in 2.5%
Poonam Patil, Babaji Ghewade, Ulhas Jadhav, Amit Toshniwal, Amisha Soni   +4 more
doaj   +2 more sources

An Atypical Presentation of Tuberculous Ascites, Severe Hyponatremia, and Acute Kidney Injury in a Young Male. [PDF]

Clin Case Rep
ABSTRACT A 25‐year‐old male who had been in good health before presenting with right lower lobe pneumonia, severe hyponatremia (Na 117 mEq/L), distension, and reduced urine output. AKI secondary to acute glomerulonephritis (GN) or interstitial nephritis was suggested by the initial workup. He was discharged for outpatient nephrology follow‐up following
Al Hariri B, Sharif M, Noor Illahi M, Eltigani AMA, Al Anbagi USM, Ahmad M.   +5 more
europepmc   +2 more sources

Mycobacterium avium Infection in a Domestic Shorthair Cat Following Subdermal Hyaluronic Acid Filler Injection. [PDF]

Vet Ophthalmol
ABSTRACT Objective To describe the diagnosis and treatment of a Mycobacterium avium (M. avium) infection in a cat following subdermal hyaluronic acid (HA) filler injection. Animal Studied A five‐year‐old spayed female domestic shorthair cat with chronic inferior lateral entropion and chronic feline atopic skin syndrome (FASS).
Bergen AE, Miller C, Eaton JS, Tomich LM, Heyward JL, Opgenorth TA.   +5 more
europepmc   +2 more sources

Cutaneous tuberculosis with features suggestive of scrofuloderma masquerading as hidradenitis suppurativa: a case report [PDF]

Therapeutic Advances in Infectious Disease
Scrofuloderma is a form of cutaneous tuberculosis that results from the spread of infection from an underlying focus, most commonly lymph nodes or bone, to the overlying skin.
Midhun Raj, Tarun Kumar Suvvari, Vimal Thomas, Anand Krishnan R. G., Aishwarya Nitin Dnyate, Ryan Chris Thaddaeus, Noel Thomas Kandathil, Tejinder Singh   +7 more
doaj   +2 more sources

Retro-inversion imparts antimycobacterial specificity to host defense peptides [PDF]

Nature Communications
Antimicrobial host defense peptides are promising alternatives to resistance prone small molecule antibiotics. To overcome the poor physiologic stability of these therapeutic candidates it is common to prepare proteolytically resistant retro-inverso ...
Hugh D. Glossop, Gebremichal Gebretsadik, Sabiha Sultana, Diptomit Biswas, Nathan A. Schacht, Neela H. Yennawar, Muzafar Ahmad Rather, Anthony D. Baughn, Scott H. Medina   +8 more
doaj   +2 more sources

The MAB_3513c gene plays a key role in intrinsic resistance of Mycobacterium abscessus to isoniazid and ethionamide [PDF]

Microbiology Spectrum
Isoniazid (INH) and ethionamide (ETH) are important antitubercular analogs that inhibit mycolic acid synthesis. However, Mycobacterium abscessus (M. abscessus) exhibits intrinsic resistance to both drugs.
Shuai Wang, Xiaofan Zhang, Xiange Fang, H. M. Adnan Hameed, Abdul Malik, Lihua Long, Yamin Gao, Cuiting Fang, Xirong Tian, Jinxing Hu, Xingyue Wang, Liqiang Feng, Tianyu Zhang   +12 more
doaj   +2 more sources

Drug induced liver injury: East versus West – a systematic review and meta-analysis [PDF]

Clinical and Molecular Hepatology, 2020
Drug induced liver injury (DILI) may be different in the East compared to the West due to differing disease prevalence, prescribing patterns and pharmacogenetic profiles.
En Xian Sarah Low, Qishi Zheng, Edwin Chan, Seng Gee Lim   +3 more
doaj   +1 more source

Antitubercular activity assessment of fluorinated chalcones, 2-aminopyridine-3-carbonitrile and 2-amino-4H-pyran-3-carbonitrile derivatives: In vitro, molecular docking and in-silico drug likeliness studies.

PLoS ONE, 2022
A series of newer previously synthesized fluorinated chalcones and their 2-amino-pyridine-3-carbonitrile and 2-amino-4H-pyran-3-carbonitrile derivatives were screened for their in vitro antitubercular activity and in silico methods.
Surendra Babu Lagu, Rajendra Prasad Yejella, Srinath Nissankararao, Richie R Bhandare, Venu Sampath Golla, Bontha Venkata Subrahmanya Lokesh, M Mukhlesur Rahman, Afzal Basha Shaik   +7 more
doaj   +2 more sources

Synthesis of 2-(6-substituted quinolin-4-yl)-1-(4-aryl-1H-1,2,3-triazol-1-yl) propan-2-ol as potential antifungal and antitubercular agents

European Journal of Medicinal Chemistry Reports, 2023
The intense pressure of resistance to antibiotics leads the whole world's health security to drastic conditions due to Mycobacterial and fungal infections.
Abhijit Shinde, Prashant P. Thakare, Yogesh Nandurkar, Manish Bhoye, Abhijit Chavan, Pravin C. Mhaske   +5 more
doaj   +1 more source

A Case Report on Disseminated Tuberculosis in a Newborn [PDF]

Pediatric Infectious Disease, 2023
Congenital tuberculosis (CTB) is a rare and challenging diagnosis with high mortality. As one of the many differentials for newborn sepsis, it should be considered when neonates deteriorate despite broad-spectrum antibiotics.
Sachin Bhagat, Mangla Sood, Parveen Bhardwaj   +2 more
doaj   +1 more source