Results 1 to 10 of about 10,695 (225)
Host Antimicrobial Peptides: The Promise of New Treatment Strategies against Tuberculosis [PDF]
Frontiers in Immunology, 2017 Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a global health emergency due to an alarming rise of antimicrobial resistance to its treatment.
Javier Arranz-Trullén +5 more
doaj +4 more sources
Drug induced liver injury: East versus West – a systematic review and meta-analysis [PDF]
Clinical and Molecular Hepatology, 2020 Drug induced liver injury (DILI) may be different in the East compared to the West due to differing disease prevalence, prescribing patterns and pharmacogenetic profiles.
En Xian Sarah Low +3 more
doaj +1 more source
PLoS ONE, 2022 A series of newer previously synthesized fluorinated chalcones and their 2-amino-pyridine-3-carbonitrile and 2-amino-4H-pyran-3-carbonitrile derivatives were screened for their in vitro antitubercular activity and in silico methods.
Surendra Babu Lagu +7 more
doaj +2 more sources
A Case Report on Disseminated Tuberculosis in a Newborn [PDF]
Pediatric Infectious Disease, 2023 Congenital tuberculosis (CTB) is a rare and challenging diagnosis with high mortality. As one of the many differentials for newborn sepsis, it should be considered when neonates deteriorate despite broad-spectrum antibiotics.
Sachin Bhagat +2 more
doaj +1 more source
Platensimycin Activity against Mycobacterial β-Ketoacyl-ACP Synthases [PDF]
, 2009 Background - There is an urgent need for the discovery and development of new drugs against Mycobacterium tuberculosis, the causative agent of tuberculosis, especially due to the recent emergence of multi-drug and extensively-drug resistant strains ...
Alistair K. Brown +5 more
core +11 more sources
Molecules, 2023 Novel antitubercular compounds are urgently needed to combat drug-resistant Mycobacterium tuberculosis (Mtb). Filamentous actinobacteria have historically been an excellent source of antitubercular drugs.
Daniel J. Watson +4 more
doaj +1 more source
European Journal of Medicinal Chemistry Reports, 2023 The intense pressure of resistance to antibiotics leads the whole world's health security to drastic conditions due to Mycobacterial and fungal infections.
Abhijit Shinde +5 more
doaj +1 more source
The challenge of managing extensively drug-resistant tuberculosis at a referral hospital in the state of São Paulo, Brazil: a report of three cases [PDF]
Jornal Brasileiro de Pneumologia, 2015 Here, we report the cases of three patients diagnosed with extensively drug-resistant tuberculosis and admitted to a referral hospital in the state of São Paulo, Brazil, showing the clinical and radiological evolution, as well as laboratory test results,
Marcos Abdo Arbex +3 more
doaj +3 more sources
Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds. [PDF]
PLoS ONE, 2015 Tuberculosis (TB) remains a worldwide problem and the need for new drugs is increasingly more urgent with the emergence of multidrug- and extensively-drug resistant TB.
Magdalena Makowska-Grzyska +13 more
doaj +1 more source
Inhalable spray-dried chondroitin sulphate microparticles: effect of different solvents on particle properties and drug activity [PDF]
, 2020 Spray-drying stands as one of the most used techniques to produce inhalable microparticles, but several parameters from both the process and the used materials affect the properties of the resulting microparticles.
Buttini, Francesca +6 more
core +1 more source