Tubercular round pneumonia simulating a mass lesion in an adult
The Egyptian Journal of Internal Medicine, 2018 Round pneumonia, a benign cause of spherical lesions seen on chest imaging, can many a times be difficult to distinguish from bronchogenic carcinomas. Although relatively less common in adults, this entity is seen in most pulmonary medicine and radiology
Ved Prakash +5 more
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Early Drug Development and Evaluation of Putative Antitubercular Compounds in the -Omics Era
Frontiers in Microbiology, 2021 Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of people worldwide.
Alina Minias +13 more
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Attenuation of Mycobacterium species through direct and macrophage mediated pathway by unsymmetrical diaryl urea [PDF]
, 2016 Tuberculosis is a major threat for mankind and the emergence of resistance strain of Mycobacterium tuberculosis (Mtb) against first line antibiotics makes it lethal for human civilization.
Charan Raja, Mamilla R. +10 more
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Synthesis of 2-oxo-azetidine derivatives of 2-amino thiazole and their biological activity [PDF]
, 2012 A new series of N-[2-(2-aminothiazolyl)ethyl]-4-(substitutedphenyl)- 3-chloro-2-oxo-1-iminoazetidine, compounds 4(a-m) have been synthesized from 2-aminothiazole as a starting material.
Samadhiya Pushkal +3 more
core +1 more source
Jornal Brasileiro de Pneumologia, 2012 A correlação entre a resistência à pirazinamida (PZA) e a resistência a outros fármacos antituberculose de primeira linha foi investigada em 395 cepas de Mycobacterium tuberculosis provenientes de espécimes clínicos, que representavam 14% do total de ...
Leila de Souza Fonseca +5 more
doaj +1 more source
Ursolic and oleanolic acids as antimicrobial and immunomodulatory compounds for tuberculosis treatment [PDF]
, 2013 BACKGROUND: New alternatives for the treatment of Tuberculosis (TB) are urgently needed and medicinal plants represent a potential option. Chamaedora tepejilote and Lantana hispida are medicinal plants from Mexico and their hexanic extracts have shown ...
Adelina Jiménez-Arellanes +9 more
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A favourable solubility of isoniazid, an antitubercular antibiotic drug, in alternative solvents [PDF]
Fluid Phase Equilibria, 2012 Abstract The sufficient solubility of isoniazid in alternative solvents obtained in this work can open new perspectives in pharmaceutical processing. Solid–liquid equilibrium (SLE) measurements have been made using a dynamic (synthetic) method.
Andreia Forte +3 more
openaire +1 more source
Drug delivery systems for potential treatment of intracellular bacterial infections. [PDF]
, 2010 Despite the advent of a considerable number of new antibiotics, treatment of intracellular pathogens still represents a major pharmaceutical challenge.
Ariza, J. (J.) +3 more
core +1 more source
Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
Pharmaceuticals, 2020 This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina +3 more
doaj +1 more source
Machine Learning Prediction of Mycobacterial Cell Wall Permeability of Drugs and Drug-like Compounds
Molecules, 2023 The cell wall of Mycobacterium tuberculosis and related organisms has a very complex and unusual organization that makes it much less permeable to nutrients and antibiotics, leading to the low activity of many potential antimycobacterial drugs against ...
Eugene V. Radchenko +3 more
doaj +1 more source