Results 41 to 50 of about 310,698 (220)

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

BMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim, Marwa Ahmed El‐Naka, Wedad M. Nageeb, Atta Ullah Khan, Noura M. Seleem, Aliaa Abdelghafar, Doaa Zamel, Yang Liu, Qigai He, Wentao Li   +9 more
wiley   +1 more source

Multiple Cutaneous Tuberculous Abscess: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2017
Cutaneous tuberculosis is a relatively rare form of extrapulmonary tuberculosis. It usually manifests secondary to haematogenous spread or from an underlying focus of infection. We report a case of multiple tuberculous abscesses without any primary focus.
Rahul Suna, Ramu Duttaluri
doaj   +1 more source

Spina ventosa: An often missed diagnosis

Journal of Global Infectious Diseases, 2021
Rare and varied presentations of tuberculosis make it difficult for treating clinicians to arrive at the diagnosis. An adolescent female presented to the orthopedic outpatient department with slowly increasing swelling over the dorsum of the hand near ...
Ankur Agarwal, Sheetal Agarwal, Savitri Singh, Sumi Nandwani   +3 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Host Antimicrobial Peptides: The Promise of New Treatment Strategies against Tuberculosis

Frontiers in Immunology, 2017
Tuberculosis (TB) continues to be a devastating infectious disease and remerges as a global health emergency due to an alarming rise of antimicrobial resistance to its treatment.
Javier Arranz-Trullén, Javier Arranz-Trullén, Lu Lu, David Pulido, Sanjib Bhakta, Ester Boix   +5 more
doaj   +1 more source

Clean Synthesis of N‐4‐Alkylamino‐7‐chloroquinoline Cyclic Imides: Influence of Lipophilicity on Antibacterial and Ecotoxicological Properties

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
For series 2a–d, there appears to be optimal activity against Klebsiella pneumoniae when lipophilicity is intermediate (log P 2.64 for 2b). Similarly, for series 2e–g, activity against Pseudomonas aeruginosa, Staphylococcus aureus and Streptococcus mutans also increases (log P 3.71 for 2f).
Agenor P. Luz‐Filho, Thais C. Silva, Matheus B. Silva, Abraão P. Sousa, Helivaldo D. S. Souza, Priscila S. V. Lima, Alexandre Almeida‐Júnior, Fábio C. Sampaio, Petrônio F. Athayde‐Filho, Gabriela F. Fiss   +9 more
wiley   +1 more source

The Synergistic Effects of the Glutathione Precursor, NAC and First-Line Antibiotics in the Granulomatous Response Against Mycobacterium tuberculosis

Frontiers in Immunology, 2018
Mycobacterium tuberculosis (M. tb), the causative bacterial agent responsible for tuberculosis (TB) continues to afflict millions of people worldwide. Although the human immune system plays a critical role in containing M.
Garrett Teskey, Ruoqiong Cao, Ruoqiong Cao, Hicret Islamoglu, Albert Medina, Chaya Prasad, Ramaa Prasad, Airani Sathananthan, Marcel Fraix, Selvakumar Subbian, Li Zhong, Li Zhong, Li Zhong, Vishwanath Venketaraman, Vishwanath Venketaraman   +14 more
doaj   +1 more source

A Review on Green Synthetic Approaches in the Development of Quinoline Analogues

ChemistrySelect, Volume 11, Issue 33, 1 September 2026.
This review highlights recent advances in environmentally friendly approaches, including metal‐free systems, solvent‐free approaches, microwave, and ultrasonic‐assisted techniques, organo‐ and biocatalysis, ionic liquids, nanoparticle catalysis, electrochemical, and photocatalytic strategies for the synthesis of quinoline scaffolds.
Demis Zelelew, Ajay Bissessur, Parvesh Singh, Hogantharanni Govender   +3 more
wiley   +1 more source

Tuberculosis of Frontal Bone—A Rare Entity: Case Report and Review of Literature

Indian Journal of Medical and Paediatric Oncology
Tuberculosis of the frontal bone is a rare entity, most commonly occurring in childhood. In situations of painless scalp swelling coupled with or without a discharging sinus that has not responded to antibiotics, a strong index of suspicion must be ...
Jeba Nazneen, Vasundhara Patil, Ujjwal Agarwal, Aashna Karbhari, Gauri Bornak, Pranjal Rai, Abhishek Mahajan   +6 more
doaj   +1 more source

Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance

Microorganisms, 2023
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), poses a global health challenge and is responsible for over a million deaths each year.
William M. Matern, Harley T. Harris, Carina Danchik, Marissa McDonald, Gopi Patel, Aashish Srivastava, Thomas R. Ioerger, Joel S. Bader, Petros C. Karakousis   +8 more
doaj   +1 more source