Results 41 to 50 of about 10,695 (225)

Confusion and Slurred Speech in a 34-Year-Old Woman from India [PDF]

, 2011
A 34-year-old woman from India, presented with episodes of confusion and progressive speech deterioration. She also had a painless neck lump, which persisted despite antibiotics.
Chandril Chugh, N. Wadhwani, José Biller   +2 more
core   +2 more sources

Spontaneous mutations conferring antibiotic resistance to antitubercular drugs at a range of concentrations in Mycobacterium smegmatis [PDF]

Drug Development Research, 2018
AbstractMycobacteria population can undergo mutations in their DNA sequence during replication, which if not repaired, would be transferred to future generations. In this study, in vitro spontaneous mutations in Mycobacterium smegmatis mc2155 (Msm) conferring resistance to isoniazid (INHr), rifampicin (RIFr), kanamycin (KANr) and streptomycin (STRr ...
Nyinoh, Iveren W, McFadden, Johnjoe
openaire   +3 more sources

Cavitating Pulmonary Tuberculosis in a 3-year-old Child: A Case Report [PDF]

Indian Journal of Respiratory Care
Cavitating pulmonary tuberculosis (PTB) frequently occurs in adults and is uncommon in children. We report a case of a 3-year-old female child who presented with complaints of fever, cough, and poor weight gain.
Pushpa Kini, Manjunath Laxminarayana, Soham Bhunia   +2 more
doaj   +1 more source

Spina ventosa: An often missed diagnosis

Journal of Global Infectious Diseases, 2021
Rare and varied presentations of tuberculosis make it difficult for treating clinicians to arrive at the diagnosis. An adolescent female presented to the orthopedic outpatient department with slowly increasing swelling over the dorsum of the hand near ...
Ankur Agarwal, Sheetal Agarwal, Savitri Singh, Sumi Nandwani   +3 more
doaj   +1 more source

Natural carriers for application in tuberculosis treatment [PDF]

, 2012
Tuberculosis remains the leading cause of preventable deaths worldwide and unsuccessful therapy is mainly due to non-compliance with very prolonged treatments, often associated with severe side-effects.
Ahmad Z, Ahmad Z, Ahmad Z, Ahmad Z, Ahmad Z, Ahsan F, Ain Q, Al-Qadi S, Ana Grenha, Anwunobi A, Armstead A, Attama A, Azarmi S, Barrow W, Beneke C, Blasi P, Borges O, Braz L, Devi N, Doherty T, Dyala’A GG, Florence A, George M, Grabovac V, Grenha A, Grenha A, Hans M, Hugo Costa, Hunter RL, Hwang SM, Lehr C-M, Lewis C, Liu Z, Lu E, Malafaya P, Martins S, Misra A, Mizoe T, Mizrahy S, Mosser D, Murata Y, Pandey R, Pandey R, Pandey R, Pinto Reis C, Ranjita S, Russell D, Smola M, Sudhakar Y, Taylor P, Yadav AB, Zara GP   +51 more
core   +1 more source

Multiple Cutaneous Tuberculous Abscess: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2017
Cutaneous tuberculosis is a relatively rare form of extrapulmonary tuberculosis. It usually manifests secondary to haematogenous spread or from an underlying focus of infection. We report a case of multiple tuberculous abscesses without any primary focus.
Rahul Suna, Ramu Duttaluri
doaj   +1 more source

Functional Whole Genome Screen of Nutrient-Starved Mycobacterium tuberculosis Identifies Genes Involved in Rifampin Tolerance

Microorganisms, 2023
Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), poses a global health challenge and is responsible for over a million deaths each year.
William M. Matern, Harley T. Harris, Carina Danchik, Marissa McDonald, Gopi Patel, Aashish Srivastava, Thomas R. Ioerger, Joel S. Bader, Petros C. Karakousis   +8 more
doaj   +1 more source

Antitubercular drugs for an old target: GSK693 as a promising InhA direct inhibitor [PDF]

, 2016
Despite being one of the first antitubercular agents identified, isoniazid (INH) is still the most prescribed drug for prophylaxis and tuberculosis (TB) treatment and, together with rifampicin, the pillars of current chemotherapy.
Martínez-Hoyos, María, Perez-Herran, Esther, Gulten, Gulcin, Encinas, Lourdes, Álvarez-Gómez, Daniel, Alvarez, Emilio, Ferrer-Bazaga, Santiago, García-Pérez, Adolfo, Ortega, Fátima, Angulo-Barturen, Iñigo, Rullas-Trincado, Joaquin, Blanco Ruano, Delia, Torres, Pedro, Castañeda, Pablo, Huss, Sophie, Fernández Menéndez, Raquel, González del Valle, Silvia, Ballell, Lluis, Barros, David, Modha, Sundip, Dhar, Neeraj, Signorino-Gelo, François, McKinney, John D., García-Bustos, Jose Francisco, Lavandera, Jose Luis, Sacchettini, James C., Jimenez, M. Soledad, Martín-Casabona, Nuria, Castro-Pichel, Julia, Mendoza-Losana, Alfonso   +29 more
core   +3 more sources

Substrate Characterization of Mycobacterial Kinase PknG Revealing PknG‐KARS‐MAPK Phosphorylation Signaling Axis in Host

iMetaMed, EarlyView.
This study employed multi‐omics approaches to investigate the regulatory mechanism of Mycobacterium PknG on host cell processes. We found that host lysine‐tRNA ligase (KARS) is a potential substrate of PknG; and PknG can regulate the immune response by catalyzing the phosphorylation of KARS at T592 and T595 sites, affecting the phosphorylation level in
Nana Tian, Shuyu Xie, Yanqing Tang, Junjie Liang, Wenhan Zhu, Tianqi Liu, Yewen Sun, Yang Yang, Luoxi Zhang, Danfeng Wang, Chuyao Lin, Jinyu Jia, Minjia Tan, Jun‐Yu Xu   +13 more
wiley   +1 more source

The Synergistic Effects of the Glutathione Precursor, NAC and First-Line Antibiotics in the Granulomatous Response Against Mycobacterium tuberculosis

Frontiers in Immunology, 2018
Mycobacterium tuberculosis (M. tb), the causative bacterial agent responsible for tuberculosis (TB) continues to afflict millions of people worldwide. Although the human immune system plays a critical role in containing M.
Garrett Teskey, Ruoqiong Cao, Ruoqiong Cao, Hicret Islamoglu, Albert Medina, Chaya Prasad, Ramaa Prasad, Airani Sathananthan, Marcel Fraix, Selvakumar Subbian, Li Zhong, Li Zhong, Li Zhong, Vishwanath Venketaraman, Vishwanath Venketaraman   +14 more
doaj   +1 more source