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Tumor immune-vascular crosstalk: synergy and translation of immune checkpoint inhibitors and anti-angiogenic agents in melanoma [PDF]

Frontiers in Immunology
Melanoma is the most aggressive form of skin cancer. Although immune checkpoint inhibitors (ICIs) have led to major therapeutic breakthroughs, monotherapy remains limited by suboptimal response rates and pronounced resistance.
Yijie Xie, Yijie Xie, I. Ho, I. Ho, Zhipeng Liu, Zhipeng Liu, Keyu Chen, Keyu Chen, Minjie Zhou, Minjie Zhou, Guodong Ha, Guodong Ha, Lincheng Duan, Lincheng Duan, Zhengyu Zhao, Zhengyu Zhao, Dingjun Cai, Dingjun Cai   +17 more
doaj   +2 more sources

First-line Advanced Cutaneous Melanoma Treatments: Where Do We Stand?

JMIR Cancer, 2021
Cutaneous melanoma has always been a dreaded diagnosis because of its high mortality rate and its proclivity for invasiveness and metastasis.
Louay S Abdulkarim, Richard J Motley
doaj   +1 more source

Effect of combining Zingiber officinale and Juglans regia extracts on Propionibacterium acnes, Staphylococcus aureus and Staphylococcus epidermidis: antibiofilm action and low toxicity

Anais da Academia Brasileira de Ciências, 2022
Objective was evaluated the therapeutic effect of Juglans regia (J) and Zingiber officinale (Z) extracts, alone or associated (Z75% + J25%, Z50% + J50% and Z25% + J75%) applied on planktonic cultures and biofilms of Propionibacterium acnes ...
LEONARDO A. DA SILVA, LUCAS P. RAMOS, TATIANE A. SILVA, SIMONE A.B. DE LAPENA, CARLOS EDUARDO R. SANTOS, AMJAD A. HASNA, ADRIANO BRESSANE, LUCIANE D. DE OLIVEIRA   +7 more
doaj   +1 more source

Common Dermatologic Disorders in Down Syndrome: Systematic Review

JMIR Dermatology, 2022
BackgroundDown syndrome (DS) has been associated with cardiovascular, gastrointestinal, and immune-related abnormalities. Several dermatologic conditions, including hidradenitis suppurativa, have also been found to be associated ...
Megan Lam, Justin Di Lu, Levi Elhadad, Cathryn Sibbald, Raed Alhusayen   +4 more
doaj   +1 more source

Prevalence of Isotretinoin Therapy in Adolescents and Young Adults With and Without Atopic Dermatitis: A Nationwide Prescription-based Population Study

Acta Dermato-Venereologica, 2023
Although isotretinoin has anti-inflammatory and immunomodulatory properties, it can exacerbate atopic dermatitis. National estimates of the extent to which patients with atopic dermatitis are affected by severe acne and isotretinoin tolerability are ...
Cathrine H. Mohn, Hege S. Blix, Anja Maria Brænd, Per Nafstad, Jon Anders Halvorsen   +4 more
doaj   +1 more source

Novel antiangiogenic agents in dermatology [PDF]

Archives of Biochemistry and Biophysics, 2011
Because angiogenesis underlies the pathogenesis of numerous conditions (cancer, psoriasis, macular degeneration), there is a pressing need for continued investigations into angiogenic signaling and potential drug targets. Antiangiogenic agents can be classified as either direct or indirect.
Ricardo L, Berrios, Jack L, Arbiser
openaire   +2 more sources

Use of psychiatric drugs in Dermatology, [PDF]

Anais Brasileiros de Dermatologia, 2020
Patients with psychocutaneous disorders often refuse psychiatric intervention in their first consultations, leaving initial management to the dermatologist.
Magda Blessmann Weber, Júlia Kanaan Recuero, Camila Saraiva Almeida   +2 more
doaj   +1 more source

Achieving hemostasis in dermatology-Part II: Topical hemostatic agents

Indian Dermatology Online Journal, 2013
Bleeding is a common occurrence during any dermatologic surgery that disrupts blood vessels. The complications of excess bleeding can include delayed wound healing, hematoma formation, infection, dehiscence, and necrosis.
Jaimie B Glick, Ravneet R Kaur, Daniel Siegel   +2 more
doaj   +1 more source

Risperidone-induced erythema multiforme minor

Indian Journal of Psychological Medicine, 2017
Antipsychotic agents are known to cause adverse cutaneous reactions. These are supposedly rare with atypical antipsychotic agents. Adverse dermatologic reactions due to antipsychotic agent risperidone are rarely reported.
Shreyas Shrikant Pendharkar, Shilpa Avinash Telgote, Amol Jadhav, Sachin Bhojne   +3 more
doaj   +1 more source

Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group. [PDF]

, 2017
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse ...
Abdallah, K., Anderson, J., Andrews, S., Arrindell, D., Ballesteros, J., Bingham, C. O., Boyer, J., Brogdon, C., Chen, D., Chonzi, D., Cotarla, I., Cunha, R., Dadu, R., Davies, M., Dawson, M., Diab, A., Dicker, Adam, Eifler, L., Ernstoff, M. S., Ferguson, A., Ferlini, C., Frankel, S., Go, W., Gochett, C., Goldberg, J., Goncalves, P., Goswami, T., Gregory, N., Gulley, J. L., Hamad, L., Hayreh, V., Helie, N., Holmes, W., Hsu, J. Y., Ibrahim, R., Kaufman, H. L., Kim, S., Lacouture, M. E., Lambotte, O., Larocca, C., LeBoeuf, N. R., Lehman, K., Lenihan, D., Ley-Acosta, S., Luke, J., McClure, J., Michelon, E., Nakamura, M., Onofrei, C., Patel, K., Piperdi, B., Puzanov, I., Rasheed, Z., Reshef, D., Riemer, J., Robert, C., Sarkeshik, M., Saylors, A., Schreiber, J., Shafer-Weaver, K., Shannon, V., Sharfman, W., Sharma, R., Sharon, E., Sherry, R., Silk, A. W., Simonson, C., Skondra, D., Suarez-Almazor, M. E., Thomas, C., Thompson, J. A., Trehu, E., Tresnan, D., Turner, M., Wang, Y., Wariabharaj, D., Waxman, I., Wiley, K., Wood, L., Zhang, L., Zheng, P.   +80 more
core   +2 more sources