Global pharmacovigilance analysis of dermatologic toxicity in EGFR-TKI–treated NSCLC: a cross-database real-world study [PDF]
IntroductionEpidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have transformed the treatment of EGFR-mutant non–small-cell lung cancer (NSCLC), significantly improving survival outcomes and quality of life compared with conventional
Natalia Sauer +3 more
doaj +2 more sources
Pharmacovigilance analysis of cutaneous adverse drug reactions for cetuximab, panitumumab, and necitumumab based on EudraVigilance and WHO VigiAccess [PDF]
IntroductionAnti-EGFR monoclonal antibodies (mAbs)--cetuximab, panitumumab, and necitumumab--are cornerstone therapies for selected solid tumors but are frequently associated with cutaneous adverse drug reactions (ADRs).
Natalia Sauer +4 more
doaj +2 more sources
Psoriasis and type 2 diabetes mellitus: epidemiology, shared mechanisms, and therapeutic implications: a narrative review [PDF]
Psoriasis is a chronic immune-mediated inflammatory disorder increasingly recognized as a systemic disease rather than an isolated cutaneous condition. In addition to its dermatologic burden, psoriasis is associated with multiple metabolic comorbidities,
Amr Molla
doaj +2 more sources
Immune checkpoint inhibitor-associated eosinophilic fasciitis: a systematic review of reported cases [PDF]
Background Eosinophilic Fasciitis (EF) is a rare immune-mediated fibrosing disorder of the fascia. Immune Checkpoint Inhibitors (ICIs) have transformed oncologic therapy but may precipitate immune-related Adverse Events (irAEs), including dermatologic ...
Yahya Argobi +2 more
doaj +3 more sources
Targeted Agents: Management of Dermatologic Toxicities
Epidermal growth factor receptor (EGFR) inhibitors are widely used in the treatment of many cancers, and the cutaneous toxicity profile associated with these agents has become prominent.
Barbara Burtness
core +3 more sources
Comparative efficacy of hemostatic agents in dermatologic surgery: A systematic review
This supplementary file contains the references included in the systematic review and meta-analysis titled “Comparative Efficacy and Safety of Hemostatic Agents in Dermatologic Surgery.” The study synthesized evidence from 12 comparative studies ...
Isabella Ribaudo, MD +7 more
doaj +2 more sources
First-line Advanced Cutaneous Melanoma Treatments: Where Do We Stand?
Cutaneous melanoma has always been a dreaded diagnosis because of its high mortality rate and its proclivity for invasiveness and metastasis.
Louay S Abdulkarim, Richard J Motley
doaj +1 more source
Objective was evaluated the therapeutic effect of Juglans regia (J) and Zingiber officinale (Z) extracts, alone or associated (Z75% + J25%, Z50% + J50% and Z25% + J75%) applied on planktonic cultures and biofilms of Propionibacterium acnes ...
LEONARDO A. DA SILVA +7 more
doaj +1 more source
Novel antiangiogenic agents in dermatology [PDF]
Because angiogenesis underlies the pathogenesis of numerous conditions (cancer, psoriasis, macular degeneration), there is a pressing need for continued investigations into angiogenic signaling and potential drug targets. Antiangiogenic agents can be classified as either direct or indirect.
Ricardo L, Berrios, Jack L, Arbiser
openaire +2 more sources
Intralesional agents in dermatology: Pros and cons
Since introduced in 1961, intralesional (IL) agent has become an essential part of the dermatological practice. The term IL referred to the direct delivery of agent percutaneously into skin lesions. This therapeutic approach is relatively safe, easy to perform and applicable for a broad range of dermatological conditions.
Sakhiya, Jagdish +7 more
openaire +2 more sources

