Results 1 to 10 of about 760,094 (316)

Monoclonal IgY antibodies: advancements and limitations for immunodiagnosis and immunotherapy applications

Therapeutic Advances in Vaccines and Immunotherapy
Due to their high specificity and scalability, Monoclonal IgY antibodies have emerged as a valuable alternative to traditional polyclonal IgY antibodies.
Ashraf A. Tabll, Yasser E. Shahein, Mohamed M. Omran, Nahla A. Hussein, Asmaa El-Shershaby, Ana Petrovic, Marija Glasnovic, Robert Smolic, Martina Smolic   +8 more
doaj   +1 more source

Monoclonal antibodies for the identification of New World Leishmania species

Memorias do Instituto Oswaldo Cruz, 1996
Monoclonal antibodies specific for selected species complexes of Leishmania have been employed for the characterization of several representative strains of Leishmania isolated from different hosts and localities in the Americas.
Gabriel Grimaldi Jr, Diane McMahon-Pratt
doaj   +1 more source

Therapeutic Monoclonal Antibodies

The Keio Journal of Medicine, 2011
Over a hundred years has passed since the discovery of the "magic bullet" serum therapy by Kitasato and Behring, the first ever therapeutic use of antibodies. More than 80 years later, the investigation of immunoglobulin structure and function and the development of cell and molecular biology introduced the production of monoclonal antibodies (MoAbs ...
openaire   +3 more sources

Monoclonal antibodies targeting sites in respiratory syncytial virus attachment G protein provide protection against RSV-A and RSV-B in mice

Nature Communications
Currently, only Palivizumab and Nirsevimab that target the respiratory syncytical virus (RSV) fusion protein are licensed for pre-treatment of infants. Glycoprotein-targeting antibodies may also provide protection against RSV.
Youri Lee, Laura Klenow, Elizabeth M. Coyle, Gabrielle Grubbs, Hana Golding, Surender Khurana   +5 more
doaj   +1 more source

Immunochemistry of human Lp[a]: characterization of monoclonal antibodies that cross-react strongly with plasminogen.

Journal of Lipid Research, 1991
Forty different monoclonal antibodies were produced from hybridomas that were raised against human Lp[a]. Of these, 14 strongly cross-reacted with plasminogen on ELISA screening assays while 16 clearly did not and 10 were only marginally cross-reactive ...
MA Lafferty, AM Salamon, DC Usher
doaj   +1 more source

Identification of Conserved Linear Epitopes on Viral Protein 2 of Foot-and-Mouth Disease Virus Serotype O by Monoclonal Antibodies 6F4.D11.B6 and 8D6.B9.C3

Antibodies
Foot-and-mouth disease (FMD) is a highly infectious disease of cloven-hoofed animals with a significant economic impact. Early diagnosis and effective prevention and control could reduce the spread of the disease which could possibly minimize economic ...
Wantanee Tommeurd, Kanyarat Thueng-in, Sirin Theerawatanasirikul, Nongnaput Tuyapala, Sukontip Poonsuk, Nantawan Petcharat, Nattarat Thangthamniyom, Porntippa Lekcharoensuk   +7 more
doaj   +1 more source

Systemic characteristic of safety profile of monoclonal antibodies used in rheumatology practice

Качественная клиническая практика, 2019
Monoclonal antibodies are highly effective medications, which made a breakthrough in medicine. Taking into consideration the properties of monoclonal antibodies safety plays a key role in “risk-benefit” assessment.
A. V. Philippova, A. S. Kolbin, E. V. Verbitskaya, S. V. Glagolev, V. A. Polivanov   +4 more
doaj   +1 more source

Treatment patterns and factors associated with discontinuation of monoclonal antibodies

SAGE Open Medicine
Background: Biological agents have revolutionized care in specialties such as oncology, immunology, infectious diseases, and genetic disorders, offering targeted actions on specific molecules or select immune cells. Monoclonal antibodies, known for their
Muzoon Matar Saleh Alkaabi, Syed Arman Rabbani, Padma GM Rao, Mai Ismail Mohamedelhassan   +3 more
doaj   +1 more source

Specific human antibodies against SARS-CoV-2 and monkeypox virus generated via a rapid construction and screening system

Immunobiology
Monoclonal antibodies are playing an increasingly important role in modern medicine. Human monoclonal antibodies have become a key focus in the development of monoclonal antibody therapeutics due to their safety.
Guanglei Gu, Jinhai Wang, Xiaoyun Hu, Xiuling Gu, Shirui Li, Hanle Li, Min Fang   +6 more
doaj   +1 more source

A new enzyme-linked immunosorbent assay with two monoclonal antibodies to specific epitopes measures human lecithin-cholesterol acyltransferase

Journal of Lipid Research, 2002
We established five monoclonal antibodies that reacted with human LCAT and recognized different epitopes on LCAT. These are mouse anti-human LCAT monoclonal antibodies designated 36487, 36454, 36442, 36405, and 36486, which react with the peptides ...
Kiichiro Kobori, Kazunori Saito, Sachiko Ito, Kazuo Kotani, Mitsuhisa Manabe, Takashi Kanno   +5 more
doaj   +1 more source