Epitope Mapping of Monoclonal and Polyclonal Antibodies Using Bacterial Cell Surface Display
, 2014 The unique property of specific high-affinity binding to more or less any target of interest has made antibodies tremendously useful in numerous applications.
Rockberg, Johan, +5 more
core +1 more source
Characterisation of two snake toxin-targeting human monoclonal immunoglobulin G antibodies expressed in tobacco plants [PDF]
, 2023 Current snakebite antivenoms are based on polyclonal animal-derived antibodies, which can neutralize snake venom toxins in envenomed victims, but which are also associated with adverse reactions.
Anna Christina Adams +10 more
core +1 more source
38227 Specific and highly potent human monoclonal antibodies against SARS-CoV-2
Journal of Clinical and Translational Science, 2021 IMPACT: We devised a new method to produce highly potent SARS-CoV2-specific that can be used to treat severely ill patients with Covid-19. OBJECTIVES/GOALS: Neutralizing antibodies against SARS-CoV-2 are thought to offer the most immediate and effective ...
Mayara Garcia de Mattos Barbosa +4 more
doaj +1 more source
Frontiers in Bioengineering and BiotechnologyThe Chinese hamster ovarian (CHO) cells serve as a common choice in biopharmaceutical production, traditionally cultivated in stirred tank bioreactors (STRs).
Xuekun Wang +41 more
doaj +1 more source
Monoclonal Antibodies as Immune Modulators for Cancer Therapy
Canadian Journal of Infectious Diseases, 1992 Monoclonal antibodies may modulate immune and/or biological responses alone, or as carriers of specific agents. Monoclonal antibodies directed against tumours may be indirectly cytotoxic by modulation of antibody-dependent, cell-mediated cytotoxicity or ...
Robert O Dillman
doaj +1 more source
Characterization of monoclonal and polyclonal antibodies to bovine enteric coronavirus: Establishment of an efficient ELISA for antigen detection in feces [PDF]
, 1989 Monoclonal antibodies to bovine enteric coronavirus (BEC) were produced. Additionally, polyclonal antibodies were made in rabbits and guinea pigs and extracted from the yolk of immunized hens.
Eichhorn, Werner, Czerny, C. P.
core
Methodological validation study of nrCE-SDS for monoclonal antibodies
生物医学转化Objective To perform methodological validation of non-reduced capillary electrophoresis-sodium dodecyl sulfate (nrCE-SDS) for monoclonal antibodies, providing a reference for the methodological validation of corresponding quality control methods in the ...
Xu Gangling +5 more
doaj +1 more source
PCSK9 monoclonal antibodies: An overview
Heart Views, 2020 PCSK9 monoclonal antibodies are novel lipid-lowering therapy that have been extensively studied in patients with hypercholesterolemia either as monotherapy or as an add-on to other LLTs.
Rasha Kaddoura +2 more
doaj +1 more source
The development and applications of polyclonal and monoclonal antibodies for the detection of illicit drugs in saliva samples [PDF]
, 2002 Anti-tetrahydrocannabinol (THC), anti-cocaine and anti-morphine polyclonal antibodies were produced. These antibodies were successfully applied to an ELISA format for the detection of THC, cocaine, and morphine in saliva samples. Monoclonal antibodies
Fanning, Lorna M.
core
Monoclonal antibodies in treatment of non-small cell lung cancer
, 2022 Battling with various types of cancerous diseases has been one of the greatest areas of national and global medical endeavors in the late 20th and during the 21st centuries.
Shahni Danesh, Sina
core