Thinking Outside the Box to Obtain the Best Antibodies! [PDF]
Monoclonal Antibodies Laboratory Department of Clinical Analysis School of Pharmaceutical Sciences São Paulo State University (UNESP), Rodovia Araraquara Jau KM01Monoclonal Antibodies Laboratory Department of Clinical Analysis School of Pharmaceutical ...
Moroz, Andrei [UNESP]
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Human monoclonal islet specific autoantibodies share features of islet cell and 64 kDa antibodies [PDF]
The first human monoclonal islet cell antibodies of the IgG class (MICA 1-6) obtained from an individual with Type 1 (insulin-dependent) diabetes mellitus were cytoplasmic islet cell antibodies selected by the indirect immunofluorescence test on pancreas
Brandt, M. +7 more
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Validation of Adapted Neutralization Assays Developed to Discriminate Anti-Rabies Virus Activity of Two Different Anti-Rabies Virus Monoclonal Antibodies Administered as a Combination [PDF]
Assessment of rabies virus (RABV) neutralizing antibodies in subjects vaccinated or injected with anti-RABV immunoglobulins is central in determination of rabies protection.
Bruno Boulanger +4 more
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Epitope Mapping of Monoclonal and Polyclonal Antibodies Using Bacterial Cell Surface Display [PDF]
The unique property of specific high-affinity binding to more or less any target of interest has made antibodies tremendously useful in numerous applications.
Rockberg, Johan, +5 more
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Delineating Molecular Mechanisms of Squamous Tissue Homeostasis and Neoplasia: Focus on p63
Mouse models have informed us that p63 is critical for normal epidermal development and homeostasis. The p53/p63/p73 family is expressed as multiple protein isoforms due to a combination of alternative promoter usage and C-terminal alternative splicing ...
Kathryn E. King +3 more
doaj +1 more source
Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate [PDF]
The majority of broadly neutralizing antibodies to hepatitis C virus (HCV) are against conformational epitopes on the E2 glycoprotein. Many of them recognize overlapping epitopes in a cluster, designated as antigenic domain B, that contains residues G530
Wenyan Wang (171659) +68 more
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Hybridoma technology; advancements, clinical significance, and future aspects
Background Hybridoma technology is one of the most common methods used to produce monoclonal antibodies. In this process, antibody-producing B lymphocytes are isolated from mice after immunizing the mice with specific antigen and are fused with immortal ...
Sanchita Mitra, Pushpa Chaudhary Tomar
doaj +1 more source
Monoclonal antibodies in treatment of non-small cell lung cancer [PDF]
Battling with various types of cancerous diseases has been one of the greatest areas of national and global medical endeavors in the late 20th and during the 21st centuries.
Shahni Danesh, Sina
core
Mouse IgG3 is highly protective against several life-threatening bacteria. This isotype is the only one among mouse IgGs that forms non-covalent oligomers, has increased functional affinity to polyvalent antigens, and efficiently agglutinates ...
Tomasz Klaus +2 more
doaj +1 more source
Differences in affinity of monoclonal and naturally acquired polyclonal antibodies against Plasmodium falciparum merozoite antigens [PDF]
Malaria is a major global cause of deaths and a vaccine is urgently needed.; We have employed the P. falciparum merozoite antigens MSP2-3D7/FC27 and AMA1, used them in ELISA, and coupled them in different ways using surface plasmon resonance (SPR) and ...
Stanisic, Danielle +41 more
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