Results 1 to 10 of about 651,038 (261)

Specific Antibody Deficiencies

Immunology and Allergy Clinics of North America, 2015
Patients with specific antibody deficiency (SAD) have a deficient immunologic response to polysaccharide antigens. Such patients experience sinopulmonary infections with increased frequency, duration, or severity compared with the general population. SAD is definitively diagnosed by immunologic challenge with a pure polysaccharide vaccine in patients 2
Luke A, Wall, Victoria R, Dimitriades, Ricardo U, Sorensen   +2 more
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Specificity of deoxycytidylate antibodies

Immunology Letters, 1981
Antibodies to deoxycytidylate (dpC) were elicited in rabbits using a thyroglobulin (Tg) conjugate of dpC. The specificity of the antibodies was determined by measuring the inhibition of the binding of [3H]dpC to the antibodies by various non-radioactive nucleotides or derivatives.
Reddy, M Vijayaraj, Jacob, TM
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Specific anti-antibodies

Experientia, 1972
Les anti-anticorps pourraient avoir des applications theerapeutiques dans certains etats allergiques, les maladies d'auto-immunisation et dans les greffes des tissues. Les auteurs montrent la possibilite de stimuler la formation des anti-anticorps specifiques contre les anticorps produits par des antigenes relativement simples comme l'albumine, le ...
N, Radoiu, F A, Zydeck, R R, Bennett
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Antibodies as specific chaperones

Biochemistry (Moscow), 2004
Protein folding is often accompanied by formation of non-native conformations leading to protein aggregation. A number of reports indicate that antibodies can facilitate folding and prevent aggregation of protein antigens. The influence of antibodies on folding is strictly antigen specific.
D N, Ermolenko, A V, Zherdev, B B, Dzantiev   +2 more
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Antibody specificity and promiscuity

Biochemical Journal, 2019
AbstractThe immune system is capable of making antibodies against anything that is foreign, yet it does not react against components of self. In that sense, a fundamental requirement of the body's immune defense is specificity. Remarkably, this ability to specifically attack foreign antigens is directed even against antigens that have not been ...
Deepti Jain, Dinakar M. Salunke
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Antimucopeptide Antibodies and Their Specificity

The Journal of Immunology, 1969
Abstract The immunochemical specificity of the common part of bacterial mucopeptide, which is composed of the polysaccharide backbone and the peptide side chains, was studied in a heterologous system consisting of soluble, nondialyzable, lysozymedigest of M. lysodeikticus cell walls as test antigen and anti-S.
M, Rolicka, J T, Park
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Stabilization of enzymes by their specific antibodies

Enzyme and Microbial Technology, 1991
In nature, increased stability of enzymes has often been found to be associated with noncovalent protein-protein interactions. Specific antibodies should be suitable for this purpose. To test this hypothesis, we used a number of model enzymes, complexed them with their specific antibodies, and exposed them and the free enzymes to low and high ...
E Y, Shami, M, Ramjeesingh, A, Rothstein, M, Zywulko   +3 more
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Specificities of antibodies to oestrogens

Journal of Steroid Biochemistry, 1972
Abstract Until recently attempts to endow antigenicity to 17β-oestradiol have invariably been made by conjugating protein (usually bovine serum albumin) via a hemisuccinate bridge to functional groups. Coupling in this manner produced antisera which unfortunately gave serious crossreactions with other naturally occurring oestrogens.
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Effects of specific antigen and specific antibody on the kinetics of in vitro antibody production

Cellular Immunology, 1980
Abstract An in vitro model system was used to probe the regulation of an ongoing antibody response. This system employed lymphocyte cell cultures prepared from the draining lymph nodes of rabbits immunized with glutaraldehyde-polymerized or heat-aggregated human serum albumin.
E J, Greene, J G, Tew, G A, Miller
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THE SPECIFICITY OF FETAL IgM: ANTIBODY OR ANTI‐ANTIBODY?

Annals of the New York Academy of Sciences, 1975
Reference materials were produced to standardize the immunoglobulin class specificity and potency of immunofluorescent anti-IgM conjugates used for diagnostic tests for congenital syphilis. In attempting to mimic essential immunologic characteristics of syphilitic and nonsyphilitic infant sera, we evaluated these sera in comparison with processed adult
C B, Reimer, C M, Black, D J, Phillips, L C, Logan, E F, Hunter, B J, Pender, B E, McGrew   +6 more
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