eLife, 2020 Antibodies are critical components of adaptive immunity, binding with high affinity to pathogenic epitopes. Antibodies undergo rigorous selection to achieve this high affinity, yet some maintain an additional basal level of low affinity, broad reactivity
Christopher T Boughter +6 more
doaj +1 more source
Structurally Mapping Antibody Repertoires
Frontiers in Immunology, 2018 Every human possesses millions of distinct antibodies. It is now possible to analyze this diversity via next-generation sequencing of immunoglobulin genes (Ig-seq).
Konrad Krawczyk +16 more
doaj +1 more source
The production of polyclonal, monoclonal and genetically-derived scFv antibody fragments for the detection of the ß-lactam antibiotic, cephalexin, in milk [PDF]
, 2006 This thesis describes the production of antibodies for the detection of cephalexin and their application in ELISA and Biacore ‘real-time’ surface plasmon resonance (SPR)-based biosensor assays.
Darmanin Sheehan, Alfredo
core +2 more sources
Fv antibodies to aflatoxin B1 derived from a pre-immunized antibody phage display library system [PDF]
, 2002 The production and characterization of recombinant antibodies to aflatoxin B[SUB1] (AFB[SUB1]), a potent mycotoxin and carcinogen is described. The antibody fragments produced were then applied for use in a surface plasmon resonance-based biosensor ...
Daly, Stephen J. +6 more
core +2 more sources
Specificity of the ChAT antibody.
, 2022 (A) Two nonoverlapping morpholinos blocked the translation of ChAT. (B) Using the same antigen, we made an anti-ChAT antibody in a rabbit. Although the background was slightly high, the antibody recognized ciliary band neurons to a similar degree as a ...
Shunsuke Yaguchi (32970) +4 more
core +1 more source
Generation and application of recombinant antibody fragments for prostate cancer detection. [PDF]
, 2010 Prostate cancer (PCa) is the most prevalent adenocarcinoma and the second highest cause of cancer-related deaths in men. Early diagnosis is required to identify the development of PCa to reduce the risk of the disease metastasising to different regions ...
Hayes, Conor
core +1 more source
Plasmodium falciparum merozoite surface protein 2: epitope mapping and fine specificity of human antibody response against non-polymorphic domains [PDF]
, 2014 Two long synthetic peptides representing the dimorphic and constant C-terminal domains of the two allelic families of Plasmodium falciparum merozoite surface proteins 2 are considered promising malaria vaccine candidates.
Kajava, Andrey V. +15 more
core +1 more source
Frontiers in Microbiology, 2017 The influence of age and maternal antibodies on the antibody responses to human respiratory syncytial virus (hRSV) glycoproteins in very young children has been a matter of controversy.
Alfonsina Trento +12 more
doaj +1 more source
Strategies for immunohistochemical protein localization using antibodies: What did we learn from neurotransmitter transporters in glial cells and neurons [PDF]
, 2016 Immunocytochemistry and Western blotting are still major methods for protein localization, but they rely on the specificity of the antibodies. Validation of antibody specificity remains challenging mostly because ideal negative controls are often ...
core +1 more source
Antibody production in transgenic plants
, 2022 S.301-318Antibodies bind with great affinity and specificity to their target antigens, allowing them to be exploited in research, medicine, agriculture, and industry.
Christou, P. +4 more
core +1 more source