Specificity and application of SOX2 antibody
Sox2 is known to play an important role in maintaining the totipotency and self-renewal of embryonic stem cells. The purpose of this study was to prepare an anti-chicken Sox2 polyclonal antibody using prokaryotic expression techniques, to evaluate its ...
Longqin Wei +11 more
doaj +1 more source
IgG Study of Blood Sera of Patients with COVID-19
The COVID-19 pandemic, which began at the end of 2019 in Wuhan, has affected 220 countries and territories to date. In the present study, we studied humoral immunity in samples of the blood sera of COVID-19 convalescents of varying severity and patients ...
Elena Kazachinskaia +10 more
doaj +1 more source
Production, characterization, and antigen specificity of recombinant 62-71-3, a candidate monoclonal antibody for rabies prophylaxis in humans [PDF]
Rabies kills many people throughout the developing world every year. The murine monoclonal antibody (mAb) 62-71-3 was recently identified for its potential application in rabies postexposure prophylaxis (PEP).
Both, L +26 more
core +1 more source
Specificity of the ChAT antibody. [PDF]
(A) Two nonoverlapping morpholinos blocked the translation of ChAT. (B) Using the same antigen, we made an anti-ChAT antibody in a rabbit. Although the background was slightly high, the antibody recognized ciliary band neurons to a similar degree as a ...
Shunsuke Yaguchi (32970) +4 more
core +1 more source
Role of hydrophobic interaction in hapten-antibody binding [PDF]
The precipitation reaction of bovine serum albumin coupled with p-azophenylleucine with homologous antibody was inhibited by several structurally related haptens. The isobutyl group substituent on alpha-carbon atom of the leucine residue contributed more
Oda, Takuzo +5 more
core +1 more source
Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity [PDF]
When purified under rigorous conditions, some murine anti-double-stranded-DNA (anti-dsDNA) antibodies actually bind chromatin rather than dsDNA. This suggests that they may actually be antinucleosome antibodies that only appear to bind dsDNA when they ...
Lambrianides, A +13 more
core +1 more source
Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania [PDF]
Objective: To evaluate the diagnostic performance of two rapid detection tests (RDTs) for HIV 1/2 in plasma and in whole blood samples. Methods: More than 15,000 study subjects above the age of two years participated in two rounds of a cohort study to ...
Geldmacher Christof +29 more
core +1 more source
IgM Antibodies Can Access Cryptic Antigens Denied to IgG: Hypothesis on Novel Binding Mechanism
Antibodies are well-known protein mediators of immunity. IgM is the primordial member and the neglected sibling of the later-evolved and more proficient IgG in regard to their therapeutic and diagnostic use.
Eric Chun Yiu Law +7 more
doaj +1 more source
Objective To analyze the factors affecting the efficacy of platelet transfusion and the specificity of HLA-Ⅰ antibodies in tumor patients. Methods Tumer patients applied for platelet transfusion from November 2019 to July 2021 in Sichuan Cancer Hospital ...
Juan SAI, Shanshan WAN, Li TIAN
doaj +1 more source
Antibodies for immunolabeling by light and electron microscopy : not for the faint hearted [PDF]
Reliable antibodies represent crucial tools in the arsenal of the cell biologist and using them to localize antigens for immunocytochemistry is one of their most important applications.
Lucocq, John Milton, Griffiths, Gareth
core +1 more source

