Results 31 to 40 of about 1,873,489 (255)

Antibody source, specificity and dilution.

, 2019
Antibody source, specificity and dilution.
Julie E. Simpson (694583), Rachel Waller (4985063), Daniel J. Fillingham (6265394), J. Robin Highley (745721), Lynne Baxter (6265391), Alejandro F. Frangi (651644), Santiago Coelho (6265397), Meghdoot Mozumder (6265400), Jose M. Pozo (4107334), Paul G. Ince (251345)   +9 more
core   +1 more source

Unconstrained generation of synthetic antibody–antigen structures to guide machine learning methodology for antibody specificity prediction

, 2022
Machine learning (ML) is a key technology for accurate prediction of antibody–antigen binding. Two orthogonal problems hinder the application of ML to antibody-specificity prediction and the benchmarking thereof: the lack of a unified ML formalization of
Hochreiter, Sepp, Prósz, Aurél, Abram, Krzysztof, Snapkov, Igor, Scheffer, Lonneke, Mehta, Brij Bhushan, Lund-Johansen, Fridtjof, Sandve, Geir Kjetil, Mathisen, Ingvild Frøberg, Slabodkin, Andrei, Miho, Enkelejda, Rawat, Puneet, Chernigovskaya, Maria, Widrich, Michael, Vu, Mai Ha, Greiff, Victor, Hobæk Haff, Ingrid, Klambauer, Günter, Olar, Axel, Robert, Philippe A., Akbar, Rahmad, Pavlović, Milena, Smorodina, Eva, Haug, Dag Trygve Tryslew   +23 more
core   +1 more source

The Complexity of Antibody Responses Elicited against the Respiratory Syncytial Virus Glycoproteins in Hospitalized Children Younger than 2 Years

Frontiers in Microbiology, 2017
The influence of age and maternal antibodies on the antibody responses to human respiratory syncytial virus (hRSV) glycoproteins in very young children has been a matter of controversy.
Alfonsina Trento, Alfonsina Trento, Rosa Rodríguez-Fernández, María I. González-Sánchez, Felipe González-Martínez, Vicente Mas, Vicente Mas, Mónica Vázquez, Mónica Vázquez, Concepción Palomo, Concepción Palomo, José A. Melero, José A. Melero   +12 more
doaj   +1 more source

The specificity of IGF signaling antibody arrays.

, 2013
The specificity of IGF signaling antibody arrays.
Ying-Qing Mao (303110), Ren-Yu Huang (303115), Zhong-Sheng Wang (303126), Xiang-Bing Zhou (303118), Yun-Ru Chen (54058), Zhi Shi (303124), Qi Zhou (7408), Ya-Feng Wang (303121), Wei-Dong Jiang (303113), Ruo-Pan Huang (303129)   +9 more
core   +1 more source

Elucidating Novel Targets for Ovarian Cancer Antibody–Drug Conjugate Development: Integrating In Silico Prediction and Surface Plasmon Resonance to Identify Targets with Enhanced Antibody Internalization Capacity

, 2023
Antibody–drug conjugates (ADCs) constitute a rapidly expanding category of biopharmaceuticals that are reshaping the landscape of targeted chemotherapy.
Jezabel Garcia-Parra, Lewis Webb Francis, Robert Steven Conlan, Deyarina Gonzalez, Emenike Kenechi Onyido, John Sinfield, Zoe Coombes, Anna Moberg, Nicole Williams, David James, Jenny Worthington   +10 more
core   +1 more source

Total antibody ICT sensitivity and specificity range*.

, 2018
Total antibody ICT sensitivity and specificity range*.
Kartika Saraswati (5007164), Stuart D. Blacksell (101742), Nicholas P. J. Day (35781), Mavuto Mukaka (85985)   +3 more
core   +1 more source

Molecular chaperone effects on recombinant yield and binding characteristics of an ABA-specific scFv in Escherichia coli

Frontiers in Bioengineering and Biotechnology
IntroductionRecombinant single‐chain variable fragments (scFvs) are promising antibody formats for cost‐effective and scalable production. However, their soluble expression in Escherichia coli is often limited by misfolding and aggregation, particularly ...
Shimiao Chen, Shimiao Chen, Shimiao Chen, Bin Shan, Bin Shan, Yican Luo, Ganhui Mo, Ganhui Mo, Ganhui Mo, Usman Rasheed, Usman Rasheed, Usman Rasheed, Lilan Lv, Lilan Lv, Xinyu Yang, Qinyu Lu, Qinyu Lu, Qinyu Lu   +17 more
doaj   +1 more source

Antibody variable region engineering for improving cancer immunotherapy

Cancer Communications, 2022
The efficacy and specificity of conventional monoclonal antibody (mAb) drugs in the clinic require further improvement. Currently, the development and application of novel antibody formats for improving cancer immunotherapy have attracted much attention.
Hantao Lou, Xuetao Cao
doaj   +1 more source

Panel demonstrating antibody specificity for SIRT1-7.

, 2015
For each sirtuin antibody a negative control (antibody diluent only) is illustrated, along with a tissue core stained with the antibody. Antibody specificity was validated via the use of blocking peptide to compete with tissue staining, or IHC on ...
Liane M. McGlynn (148841), Euan J. Dickson (762435), Alasdair I. MacDonald (762433), C. Ross Carter (762436), Simon McCluney (762431), Nigel B. Jamieson (762432), Paul G. Shiels (125083), Colin J. McKay (762437), Jackie Thomson (273709), Karin Oien (762434)   +9 more
core   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source