Results 51 to 60 of about 1,873,489 (255)

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

The production of polyclonal, monoclonal and genetically-derived scFv antibody fragments for the detection of the ß-lactam antibiotic, cephalexin, in milk [PDF]

, 2006
This thesis describes the production of antibodies for the detection of cephalexin and their application in ELISA and Biacore ‘real-time’ surface plasmon resonance (SPR)-based biosensor assays.
Darmanin Sheehan, Alfredo
core   +2 more sources

Low specificity of determine HIV1/2 RDT using whole blood in south west Tanzania [PDF]

, 2012
Objective: To evaluate the diagnostic performance of two rapid detection tests (RDTs) for HIV 1/2 in plasma and in whole blood samples. Methods: More than 15,000 study subjects above the age of two years participated in two rounds of a cohort study to ...
Geldmacher Christof, Petra Clowes, Elmar Saathoff, Leonard Maboko, Wolfram Mwalongo, Clowes, Petra, Hoelscher, Michael, Kroidl, Arne L., Geldmacher, Christof, Michael Hoelscher, Arne L Kroidl, Kroidl Arne L., Hoelscher Michael, Harun Machibya, Kroidl, Inge, Machibya Harun, Machibya, Harun, Saathoff, Elmar, Inge Kroidl, Maganga, Lucas, Kroidl Inge, Maganga Lucas, Mwalongo Wolfram, Christof Geldmacher, Maboko Leonard, Mwalongo, Wolfram, Saathoff Elmar, Maboko, Leonard, Lucas Maganga, Clowes Petra   +29 more
core   +2 more sources

Limited Specificity of Serologic Tests for SARS-CoV-2 Antibody Detection, Benin

Emerging Infectious Diseases, 2021
We used commercially available ELISAs to test 68 samples from coronavirus disease cases and prepandemic controls from Benin. We noted
Anges Yadouleton, Anna-Lena Sander, Andres Moreira-Soto, Carine Tchibozo, Gildas Hounkanrin, Yvette Badou, Carlo Fischer, Nina Krause, Petas Akogbeto, Edmilson F. de Oliveira Filho, Anges Dossou, Sebastian Brünink, Melchior A. Joël Aïssi, Mamoudou Harouna Djingarey, Benjamin Hounkpatin, Michael Nagel, Jan Felix Drexler   +16 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Toxin specificity of the polyclonal antibody tested by direct ELISA.

, 2013
Toxin specificity of the polyclonal antibody tested by direct ELISA.
Xiaohua He (361530), Robert E. Mandrell (37624), Reuven Rasooly (394508), Stephanie Patfield (459595), Robert Hnasko (374544)   +4 more
core   +1 more source

Antibody-drug conjugates for cancer therapy

, 2020
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Antibody–drug conjugates (ADCs) are novel drugs that exploit the specificity of a monoclonal antibody (mAb) to reach target antigens expressed on cancer cells for the delivery of a potent ...
Sagun Parakh (9493061), Umbreen Hafeez (9474611), Andrew Scott (9483443), Hui Gan (9477872)   +3 more
core   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Specificity and overlap in gene segment-defined antibody repertoires

BMC Genomics, 2005
Background To date several studies have sought to catalog the full suite of antibodies that humans naturally produce against single antigens or other specificities (repertoire).
Arnaout Ramy A
doaj   +1 more source