Characterization of Primate Antibody Responses to Administered Murine Monoclonal Immunoglobulin
The International Journal of Biological Markers, 1990 Murine monoclonal antibodies (MAb) are currently being assessed for their utility as tools in cancer management. Anti-murine immunoglobulin responses have been observed in many patients receiving monoclonal antibody treatment. In this study, we evaluated
D.E. Milenic +3 more
doaj +1 more source
A new monoclonal antibody detects downregulation of protein tyrosine phosphatase receptor type γ in chronic myeloid leukemia patients [PDF]
, 2017 Background: Protein tyrosine phosphatase receptor gamma (PTPRG) is a ubiquitously expressed member of the protein tyrosine phosphatase family known to act as a tumor suppressor gene in many different neoplasms with mechanisms of inactivation including ...
Al Sayab, Ali +15 more
core +3 more sources
Donor specific antibodies after transplantation [PDF]
Pediatric Transplantation, 2011 Platt JL, Cascalho M. Donor specific antibodies after transplantation. Pediatr Transplantation 2011: 15: 686–690. © 2011 John Wiley & Sons A/S.Abstract: The detection of donor‐specific antibodies after organ transplantation might provide an incisive way to monitor allo‐specific immunity and predict graft outcome.
Platt, Jeffrey L., Cascalho, Marilia
openaire +3 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Doses of Immunogen Contribute to Specificity Spectrums of Antibodies against Aflatoxin
Toxins, 2017 Research about antibody specificity spectra was conducted to develop single-specific antibodies or broad-specific antibodies. Aflatoxins, as one class of high-toxicity mycotoxins, were selected as the research targets to investigate the effect of the ...
Peiwu Li +9 more
doaj +1 more source
A Novel Sensitive Immunoassay Targeting the 5-Methylthio-d-Xylofuranose-Lipoarabinomannan Epitope Meets the WHO's Performance Target for Tuberculosis Diagnosis. [PDF]
, 2018 The only currently commercialized point-of-care assay for tuberculosis (TB) that measures lipoarabinomannan (LAM) in urine (Alere LF-LAM) has insufficient sensitivity.
Broger, Tobias +15 more
core
Detection of myositis-specific antibodies [PDF]
Annals of the Rheumatic Diseases, 2019 It was with much interest that we read the recent European League Against Rheumatism/American College of Rheumatology classification criteria for idiopathic inflammatory myopathies.1 These criteria include Jo-1 autoantibodies, and the authors discussed that future updates of the criteria should also include the more recently identified myositis ...
Jean-Baptiste, Vulsteke +10 more
openaire +2 more sources
Fetal Brain Tumor Harboring a Unique ROCK1::BRAF Fusion
Pediatric Blood &Cancer, EarlyView.
Marllon Cindra Sant'Ana +8 more
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Serological responses and biomarker evaluation in mice and pigs exposed to tsetse fly bites [PDF]
, 2014 Background: Tsetse flies are obligate blood-feeding insects that transmit African trypanosomes responsible for human sleeping sickness and nagana in livestock.
Caljon, Guy +6 more
core +9 more sources