Results 61 to 70 of about 7,236 (180)

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
wiley   +1 more source

Papulo necrotic tuberculid :An imitator

Indian Journal of Dermatology, 2005
A 22 year old female presented with asymptomatic papules, pustules and crusted lesions appearing in crops over the extensor aspect of both upper and lower limbs, palms and soles and sun exposed part of the back.
Sirka C, Jena S, Padhi T, Mishra S, Mohanty P   +4 more
doaj  

The Capacity of Mycobacterium tuberculosis To Survive Iron Starvation Might Enable It To Persist in Iron-Deprived Microenvironments of Human Granulomas

mBio, 2017
This study was conducted to investigate the role of iron deprivation in the persistence of Mycobacterium tuberculosis. We present evidence of iron restriction in human necrotic granulomas and demonstrate that under iron starvation M.
Krishna Kurthkoti, Hamel Amin, Mohlopheni J. Marakalala, Saleena Ghanny, Selvakumar Subbian, Alexandra Sakatos, Jonathan Livny, Sarah M. Fortune, Michael Berney, G. Marcela Rodriguez   +9 more
doaj   +1 more source

Tubercular arthritis of the elbow joint following olecranon fracture fixation and the role of TGF-beta in its pathogenesis

Chinese Journal of Traumatology, 2013
【Abstract】Tuberculosis (TB) occurring after a closed bone fracture in the patient with no history of TB and no evidence of TB infection at the time of initial fracture is a rare entity.
Habib Masood, Tanwar Yashwant Singh, Jaiswal Atin, Arya Rajender Kumar   +3 more
doaj  

Pulmonary infection by Mycobacterium riyadhense: first case report in United Arab Emirates

Frontiers in Medicine
Mycobacterium riyadhense is an emerging slowly growing species that belongs to the group of nontuberculous mycobacteria (NTM) with approximately 20 cases reported worldwide.
Batool A. Sawan, Leen O. Saleh, Dina Z. Al Shaltouni, Mohammad A. Sawan, Shefa Gawish, Samar Ahmed, Julio Gomez-Seco, Michael E. Otim   +7 more
doaj   +1 more source

Pulmonary nocardiosis masquerading renascence of tuberculosis in an immunocompetent host: a case report from Nepal

BMC Research Notes, 2018
Background Pulmonary nocardiosis is an opportunistic infection in an immunocompromised patient; however, often neglected in the immunocompetent patient from the diagnosis considerations.
Priyatam Khadka, Ramesh Bahadur Basnet, Basista Parsad Rijal, Jeevan Bahadur Sherchand   +3 more
doaj   +1 more source

Diagnostic delay in ankle and foot tuberculosis resulting in tuberculoma and tuberculous meningitis in a middle-aged female: A case report

SAGE Open Medical Case Reports
A middle-aged woman presents with chronic foot arthritis which progressed to a non-healing ulcer, which was unresponsive to conventional antibiotics and debridement.
Hedwiga F Swai, Sibtain M Moledina, Sylvia B Nsato, Amina Mgunya, Joan Rugemalila, Veridiana Byemelwa, Sharon Ismail, Pauline Chale, Luth Mwapule, Alex Masao, Jude Tarimo, Amunga Meda, Fatuma Muhali, May Shoo, Eva Uiso, Stella Rwezaura, Eliaichi Minja, Deogratius Beda, Sarah K Nyagabona, Onesmo Kisanga, Sayan Salehe, Faraja Chiwanga, Said Mwemba, John Rwegasha, Grace Shayo   +24 more
doaj   +1 more source

The Effect of Combining Natural Terpenes and Antituberculous Agents against Reference and Clinical Mycobacterium tuberculosis Strains

Molecules, 2018
Background: On account of emergence of multi- and extensively drug-resistant Mycobacterium tuberculosis (Mtb) strains, combinations of drugs with natural compounds were tested to search for antibiotic activity enhancers. In this work we studied terpenes (
Elwira Sieniawska, Rafal Sawicki, Marta Swatko-Ossor, Agnieszka Napiorkowska, Agata Przekora, Grazyna Ginalska, Marta Swatko-Ossor, Ewa Augustynowicz-Kopec   +7 more
doaj   +1 more source

Dictyosteliumdiscoideum–Mycobacterium marinum infection model: a powerful high-throughput screening platform for anti-infective compounds

Frontiers in Microbiology
Tuberculosis is among the world’s deadliest diseases, causing approximately 2 million deaths annually. The urgent need for new antitubercular drugs has been intensified by the rise of drug-resistant strains.
Jahn Nitschke, Nabil Hanna, Thierry Soldati   +2 more
doaj   +1 more source

Melioidosis: misdiagnosed in Nepal

BMC Infectious Diseases, 2019
Background Melioidosis is a life-threatening infectious disease that is caused by gram negative bacteria Burkholderia pseudomallei. This bacteria occurs as an environmental saprophyte typically in endemic regions of south-east Asia and northern Australia.
Neha Shrestha, Mahesh Adhikari, Vivek Pant, Suman Baral, Anjan Shrestha, Buddha Basnyat, Sangita Sharma, Jeevan Bahadur Sherchand   +7 more
doaj   +1 more source