Results 81 to 90 of about 10,695 (225)
This study was conducted to investigate the role of iron deprivation in the persistence of Mycobacterium tuberculosis. We present evidence of iron restriction in human necrotic granulomas and demonstrate that under iron starvation M.
Krishna Kurthkoti +9 more
doaj +1 more source
Sixteen homologs of L-HON were synthesized and their in vitro activity against M. tuberculosis was tested. From such results, L-HON was classified as a member of the group which is relatively low in molecular weight and active only against M. tuberculosis.
openaire +2 more sources
An Unusual Presentation of Spinal Tuberculosis Masquerading as Pyogenic Meningitis: A Case Report
Background Spinal tuberculosis (TB), though accounting for up to 50% of skeletal TB cases, typically presents insidiously with back pain, kyphotic deformity, or neurological deficits. Atypical presentations, including initial neutrophilic pleocytosis in cerebrospinal fluid (CSF), can mimic bacterial meningitis and complicate diagnosis.
Parackrama Karunathilake +6 more
wiley +1 more source
Papulo necrotic tuberculid :An imitator
A 22 year old female presented with asymptomatic papules, pustules and crusted lesions appearing in crops over the extensor aspect of both upper and lower limbs, palms and soles and sun exposed part of the back.
Sirka C +4 more
doaj
(E)-N'-(2, 4-dihydroxybenzylidene)nicotinohydrazide and its Metal Complexes: Synthesis, Characterisation and Antitubercular Activity [PDF]
Nicotinic acid hydrazide and 2,4-dihydoxylbenzaldehyde were condensed at 20 °C to form an acylhydrazone (H3L1) with ONO coordination pattern. The structure of the acylhydrazone was elucidated by using CHN analyzer, ESI mass spectrometry, IR, 1H NMR, 13C ...
Adekoya, J. A.
core
We report a case of hemophagocytic lymphohistiocytosis (HLH) secondary to disseminated Bacillus Calmette–Guérin (BCG) infection in an 80‐year‐old man treated with intravesical BCG for non–muscle‐invasive bladder cancer. The patient presented with several weeks of constitutional symptoms including night sweats, fatigue, weight loss, confusion, and ...
Kaitlin Quinlan +4 more
wiley +1 more source
MmpL3 is the flippase for mycolic acids in mycobacteria [PDF]
The defining feature of the mycobacterial outer membrane (OM) is the presence of mycolic acids (MAs), which, in part, render the bilayer extremely hydrophobic and impermeable to external insults, including many antibiotics.
Chng, Shu-Sin +3 more
core +1 more source
Analysis of a Mathematical Model on the Dynamics of TB–HCV Coinfection With Medication
This study employs a deterministic model that describes the combined dynamics of TB and HCV aimed at determining the impact of medication in the management of TB–HCV coinfection. The analytical and numerical analyses indicate that if the TB–HCV coinfection effective reproduction number is less than unity, the absence of both TB and HCV infections ...
Kizito Mohammed +3 more
wiley +1 more source
Synthesis of hexahydrofuro[3,2-c]quinoline, a martinelline type analogue and investigation of its biological activity [PDF]
2015-2016 > Academic research: refereed > Publication in refereed journalVersion of ...
C.-H. Cheng +6 more
core +1 more source
The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase [PDF]
EtaA is a newly identified FAD-containing monooxygenase that is responsible for activation of several thioamide prodrugs in Mycobacterium tuberculosis.
Fortin, R +3 more
core +2 more sources

