Results 91 to 100 of about 10,695 (225)

Pulmonary nocardiosis masquerading renascence of tuberculosis in an immunocompetent host: a case report from Nepal

BMC Research Notes, 2018
Background Pulmonary nocardiosis is an opportunistic infection in an immunocompromised patient; however, often neglected in the immunocompetent patient from the diagnosis considerations.
Priyatam Khadka, Ramesh Bahadur Basnet, Basista Parsad Rijal, Jeevan Bahadur Sherchand   +3 more
doaj   +1 more source

Osteoarticular Tuberculosis: a Secondary Manifestations to Tuberculous Pleural Effusion [PDF]

, 2014
Tuberculosis appears to be increasing throughout the world after years of continuous decline, despite the introduction of effective chemotherapy. This resurgence is related to the increasing number of patients immunocompromised by chemotherapeutic agents
Rumende, C. M. (Cleopas), Setyohadi, B. (Bambang), Singh, G. (Gurmeet)   +2 more
core  

Design, synthesis and biologival evaluation of novel isoniazid derivatives with potente antitubercular activity [PDF]

, 2014
The disturbing emergence of multidrug-resistant strains of Mycobacterium tuberculosis (Mtb) has been driving the scientific community to urgently search for new and efficient antitubercular drugs.
Aires-de-Sousa, João, Correia, Henrique E., Elvas Leitao, Ruben, Kovalishyn, Vasyl, Latino, Diogo A. R. S., Martins, Filomena, Miranda, Vanessa, Ramos, Jorge, Reis, Marina, Santos, Lídia, Santos, Susana, Ventura, Cristina, Vitorino, Susana, Viveiros, Miguel   +13 more
core   +1 more source

A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis. [PDF]

, 2017
Pyrazinamide (PZA) is an important first-line drug in all existing and new tuberculosis (TB) treatment regimens. PZA-resistance in M. tuberculosis is increasing, especially among M/XDR cases.
Catanzaro, A, Catanzaro, D, Fink, L, Jackson, RL, Pettigrove, M, Ramirez-Busby, SM, Rodwell, TC, Valafar, F   +7 more
core   +1 more source

Pulmonary infection by Mycobacterium riyadhense: first case report in United Arab Emirates

Frontiers in Medicine
Mycobacterium riyadhense is an emerging slowly growing species that belongs to the group of nontuberculous mycobacteria (NTM) with approximately 20 cases reported worldwide.
Batool A. Sawan, Leen O. Saleh, Dina Z. Al Shaltouni, Mohammad A. Sawan, Shefa Gawish, Samar Ahmed, Julio Gomez-Seco, Michael E. Otim   +7 more
doaj   +1 more source

The Effect of Combining Natural Terpenes and Antituberculous Agents against Reference and Clinical Mycobacterium tuberculosis Strains

Molecules, 2018
Background: On account of emergence of multi- and extensively drug-resistant Mycobacterium tuberculosis (Mtb) strains, combinations of drugs with natural compounds were tested to search for antibiotic activity enhancers. In this work we studied terpenes (
Elwira Sieniawska, Rafal Sawicki, Marta Swatko-Ossor, Agnieszka Napiorkowska, Agata Przekora, Grazyna Ginalska, Marta Swatko-Ossor, Ewa Augustynowicz-Kopec   +7 more
doaj   +1 more source

Exploration of the chemistry and biological properties of pyrimidine as a privileged pharmacophore in therapeutics [PDF]

, 2015
The pyrimidine moiety is one of the most widespread heterocycles in biologically occurring compounds, such as nucleic acids components (uracil, thymine and cytosine) and vitamin B1.
Ajani, Olayinka O.
core   +1 more source

Diagnostic delay in ankle and foot tuberculosis resulting in tuberculoma and tuberculous meningitis in a middle-aged female: A case report

SAGE Open Medical Case Reports
A middle-aged woman presents with chronic foot arthritis which progressed to a non-healing ulcer, which was unresponsive to conventional antibiotics and debridement.
Hedwiga F Swai, Sibtain M Moledina, Sylvia B Nsato, Amina Mgunya, Joan Rugemalila, Veridiana Byemelwa, Sharon Ismail, Pauline Chale, Luth Mwapule, Alex Masao, Jude Tarimo, Amunga Meda, Fatuma Muhali, May Shoo, Eva Uiso, Stella Rwezaura, Eliaichi Minja, Deogratius Beda, Sarah K Nyagabona, Onesmo Kisanga, Sayan Salehe, Faraja Chiwanga, Said Mwemba, John Rwegasha, Grace Shayo   +24 more
doaj   +1 more source

Melioidosis: misdiagnosed in Nepal

BMC Infectious Diseases, 2019
Background Melioidosis is a life-threatening infectious disease that is caused by gram negative bacteria Burkholderia pseudomallei. This bacteria occurs as an environmental saprophyte typically in endemic regions of south-east Asia and northern Australia.
Neha Shrestha, Mahesh Adhikari, Vivek Pant, Suman Baral, Anjan Shrestha, Buddha Basnyat, Sangita Sharma, Jeevan Bahadur Sherchand   +7 more
doaj   +1 more source

δ-Hydroxy-γ-oxo-L-norvaline, a New Antitubercular Antibiotic. (2). Synthetic Studies.

Chemical and Pharmaceutical Bulletin, 1960
The structure of δ-hydroxy-γ-oxo-L-norvaline was proposed for the new antibiotic, HON. This compound was synthesized through two different routes. Optical resolution of the racemate was achieved by fractional crystallization of brucine salts of N-acetyl-δ-hydroxy-γ-oxo-DL-norvaline.
openaire   +2 more sources