Erythema induratum of bazin – Skin lesions with pyrexia of unknown origin undiagnosed for 4 years
International Journal of Mycobacteriology, 2022 Erythema induratum of Bazin is characterized by chronic, tender, erythematous, indurated subcutaneous nodules on the lower extremities caused by tuberculin hypersensitivity.
Mansoor C Abdulla
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A favourable solubility of isoniazid, an antitubercular antibiotic drug, in alternative solvents [PDF]
Fluid Phase Equilibria, 2012 Abstract The sufficient solubility of isoniazid in alternative solvents obtained in this work can open new perspectives in pharmaceutical processing. Solid–liquid equilibrium (SLE) measurements have been made using a dynamic (synthetic) method.
Andreia Forte +3 more
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Tubercular round pneumonia simulating a mass lesion in an adult
The Egyptian Journal of Internal Medicine, 2018 Round pneumonia, a benign cause of spherical lesions seen on chest imaging, can many a times be difficult to distinguish from bronchogenic carcinomas. Although relatively less common in adults, this entity is seen in most pulmonary medicine and radiology
Ved Prakash +5 more
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Molecules, 2022 Natural and synthetic β-lactam derivatives constitute an interesting class of compounds due to their diverse biological activity. Mostly used as antibiotics, they were also found to have antitubercular, anticancer and antidiabetic activities, among ...
Faïza Diaba +2 more
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Early Drug Development and Evaluation of Putative Antitubercular Compounds in the -Omics Era
Frontiers in Microbiology, 2021 Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of people worldwide.
Alina Minias +13 more
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Spontaneous mutations conferring antibiotic resistance to antitubercular drugs at a range of concentrations in Mycobacterium smegmatis [PDF]
Drug Development Research, 2018 Abstract Mycobacteria populations can undergo mutations in their DNA sequence during replication, which if not repaired would be transferred to future generations. Earlier studies have tackled the estimation of mutation rate in mycobacteria at fixed concentrations.
Nyinoh, Iveren W, McFadden, Johnjoe
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Jornal Brasileiro de Pneumologia, 2012 A correlação entre a resistência à pirazinamida (PZA) e a resistência a outros fármacos antituberculose de primeira linha foi investigada em 395 cepas de Mycobacterium tuberculosis provenientes de espécimes clínicos, que representavam 14% do total de ...
Leila de Souza Fonseca +5 more
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Inhaled microparticles of antitubercular antibiotic for in vitro and in vivo alveolar macrophage targeting and activation of phagocytosis [PDF]
The Journal of Antibiotics, 2014 Tuberculosis (TB) is a chronic infectious disease with increasing incidence of drug resistance. Oral treatment for TB and multidrug resistance-TB can have serious side effects. The causative agent of TB, Mycobacterium tuberculosis, resides in alveolar macrophages (AMs).
Rajesh, Parikh +3 more
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Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents
Pharmaceuticals, 2020 This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina +3 more
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Machine Learning Prediction of Mycobacterial Cell Wall Permeability of Drugs and Drug-like Compounds
Molecules, 2023 The cell wall of Mycobacterium tuberculosis and related organisms has a very complex and unusual organization that makes it much less permeable to nutrients and antibiotics, leading to the low activity of many potential antimycobacterial drugs against ...
Eugene V. Radchenko +3 more
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