Results 21 to 30 of about 7,186 (131)

Tubercular round pneumonia simulating a mass lesion in an adult

The Egyptian Journal of Internal Medicine, 2018
Round pneumonia, a benign cause of spherical lesions seen on chest imaging, can many a times be difficult to distinguish from bronchogenic carcinomas. Although relatively less common in adults, this entity is seen in most pulmonary medicine and radiology
Ved Prakash, Ajay K Verma, Ankit Bhatia, Arpita Singh, Surya Kant, Abhijeet Singh   +5 more
doaj   +1 more source

Cytotoxic Assessment of 3,3-Dichloro-β-Lactams Prepared through Microwave-Assisted Benzylic C-H Activation from Benzyl-Tethered Trichloroacetamides Catalyzed by RuCl₂(PPh₃)₃

Molecules, 2022
Natural and synthetic β-lactam derivatives constitute an interesting class of compounds due to their diverse biological activity. Mostly used as antibiotics, they were also found to have antitubercular, anticancer and antidiabetic activities, among ...
Faïza Diaba, Alexandra G. Sandor, María del Carmen Morán   +2 more
doaj   +1 more source

Early Drug Development and Evaluation of Putative Antitubercular Compounds in the -Omics Era

Frontiers in Microbiology, 2021
Tuberculosis (TB) is an infectious disease caused by the bacterium Mycobacterium tuberculosis. According to the WHO, the disease is one of the top 10 causes of death of people worldwide.
Alina Minias, Lidia Żukowska, Lidia Żukowska, Ewelina Lechowicz, Ewelina Lechowicz, Filip Gąsior, Filip Gąsior, Agnieszka Knast, Agnieszka Knast, Sabina Podlewska, Sabina Podlewska, Daria Zygała, Daria Zygała, Jarosław Dziadek   +13 more
doaj   +1 more source

Correlação entre a resistência a pirazinamida e a resistência a outros fármacos antituberculose em cepas de Mycobacterium tuberculosis isoladas em um hospital de referência Correlation between resistance to pyrazinamide and resistance to other antituberculosis drugs in Mycobacterium tuberculosis strains isolated at a referral hospital

Jornal Brasileiro de Pneumologia, 2012
A correlação entre a resistência à pirazinamida (PZA) e a resistência a outros fármacos antituberculose de primeira linha foi investigada em 395 cepas de Mycobacterium tuberculosis provenientes de espécimes clínicos, que representavam 14% do total de ...
Leila de Souza Fonseca, Anna Grazia Marsico, Gisele Betzler de Oliveira Vieira, Rafael da Silva Duarte, Maria Helena Féres Saad, Fernanda de Carvalho Queiroz Mello   +5 more
doaj   +1 more source

Clinically Relevant Interactions between Atypical Antipsychotics and Anti-Infective Agents

Pharmaceuticals, 2020
This is a comprehensive review of the literature on drug interactions (DIs) between atypical antipsychotics and anti-infective agents that focuses on those DIs with the potential to be clinically relevant and classifies them as pharmacokinetic (PK) or ...
Edoardo Spina, Maria Antonietta Barbieri, Giuseppe Cicala, Jose de Leon   +3 more
doaj   +1 more source

Machine Learning Prediction of Mycobacterial Cell Wall Permeability of Drugs and Drug-like Compounds

Molecules, 2023
The cell wall of Mycobacterium tuberculosis and related organisms has a very complex and unusual organization that makes it much less permeable to nutrients and antibiotics, leading to the low activity of many potential antimycobacterial drugs against ...
Eugene V. Radchenko, Grigory V. Antonyan, Stanislav K. Ignatov, Vladimir A. Palyulin   +3 more
doaj   +1 more source

Cavitating Pulmonary Tuberculosis in a 3-year-old Child: A Case Report [PDF]

Indian Journal of Respiratory Care
Cavitating pulmonary tuberculosis (PTB) frequently occurs in adults and is uncommon in children. We report a case of a 3-year-old female child who presented with complaints of fever, cough, and poor weight gain.
Pushpa Kini, Manjunath Laxminarayana, Soham Bhunia   +2 more
doaj   +1 more source

Multiple Cutaneous Tuberculous Abscess: A Case Report [PDF]

Journal of Clinical and Diagnostic Research, 2017
Cutaneous tuberculosis is a relatively rare form of extrapulmonary tuberculosis. It usually manifests secondary to haematogenous spread or from an underlying focus of infection. We report a case of multiple tuberculous abscesses without any primary focus.
Rahul Suna, Ramu Duttaluri
doaj   +1 more source

Spina ventosa: An often missed diagnosis

Journal of Global Infectious Diseases, 2021
Rare and varied presentations of tuberculosis make it difficult for treating clinicians to arrive at the diagnosis. An adolescent female presented to the orthopedic outpatient department with slowly increasing swelling over the dorsum of the hand near ...
Ankur Agarwal, Sheetal Agarwal, Savitri Singh, Sumi Nandwani   +3 more
doaj   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

Advanced Healthcare Materials, Volume 15, Issue 21, 5 June 2026.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales, Cesar Augusto Roque‐Borda, Ana Carolina Cerqueira Negri, Oswaldo Ramirez Delgado, Letícia Oliveira Catarin Nunes, Flávia Aparecida Resende, Hernane Barud, Norival Alves Santos‐Filho, Saulo Santesso Garrido, Karen Cristina Oliveira, Alexandra Ivo de Medeiros, Rafael Miguel Sábio, Fernando Rogério Pavan   +12 more
wiley   +1 more source