Results 231 to 240 of about 2,467,702 (298)
Severe Scrotal Cellulitis in a Young Man
JEADV Clinical Practice, EarlyView.
Hamad El Hajj +3 more
wiley +1 more source
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
Mass Spectrometry Reviews, EarlyView.ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
EVALUATION OF OUR PATIENTS WITH ACUTE VIRAL HEPATITIS
The Turkish Journal of Gastroenterology, 1994 Mehmet İŞLER +3 more
doaj
Molecular Carcinogenesis, EarlyView.ABSTRACT Hypoxia and nutrient deprivation are fundamental drivers of tumor aggressiveness and therapeutic resistance in hepatocellular carcinoma (HCC). While the involvement of neural components in the tumor microenvironment (TME) is increasingly recognized, the molecular transducers linking metabolic stress to neuron–tumor crosstalk remain elusive ...
Taehyun Park +5 more
wiley +1 more source
Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care
Pediatric Investigation, EarlyView.This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley +1 more source
Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions
Portal Hypertension &Cirrhosis, EarlyView.This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley +1 more source
INTRAFAMILIAL TRANSMISSION OF HEPATITIS C VIRUS INFECTION
The Turkish Journal of Gastroenterology, 1994 Sedat ERTEM +4 more
doaj
Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications
Portal Hypertension &Cirrhosis, EarlyView.This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf +8 more
wiley +1 more source
Portal Hypertension &Cirrhosis, EarlyView.Sarcopenia is common in patients with cirrhosis and contributes to poor prognosis. This study investigated whether transjugular intrahepatic portosystemic shunt (TIPS) is associated with improvement in skeletal muscle mass and whether such improvement translates into better transplant‐free survival in patients with cirrhosis and low skeletal muscle ...
Qinnian Li +5 more
wiley +1 more source