Real World Use of the IL‐36 Receptor Antagonist Spesolimab: A Systematic Review and Analysis
ABSTRACT Background Spesolimab, an interleukin‐36 receptor antagonist, is approved for the treatment and prevention of generalised pustular psoriasis (GPP) flares. Its use has increasingly been reported in real‐world settings for both GPP and other inflammatory dermatoses.
Sophia A. Mense +4 more
wiley +1 more source
Trends in the etiology of acute insult and underlying chronic liver disease in patients with acute-on-chronic liver failure: A retrospective study in Southwest China (2020-2023). [PDF]
Fang Y +5 more
europepmc +1 more source
ABSTRACT The impacts of cardiometabolic risk factors (CMRFs) and the biomarkers on disease severity in metabolic dysfunction‐associated steatotic liver disease (MASLD) remain elusive. Accordingly, a multicenter study by recruiting MASLD patients from a nationwide registry database was conducted with a total of 2882 MASLD patients (54.1% males, mean age
Jee‐Fu Huang +14 more
wiley +1 more source
Dimethyl Fumarate-Associated Acute Hepatocellular Injury Assessed for Causality Using the Updated RUCAM: A Biopsy-Supported Case Report. [PDF]
Lavon O, Salameh M.
europepmc +1 more source
Admission Gut and Plasma-Derived Signatures Associated With Severity and 90-day Outcome in Hepatitis A-Related and Drug-Induced Acute Liver Failure. [PDF]
Saxena A +7 more
europepmc +1 more source
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Severe Scrotal Cellulitis in a Young Man
JEADV Clinical Practice, EarlyView.
Hamad El Hajj +3 more
wiley +1 more source
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Hepatitis A and E in rural northern India: clinico-epidemiological and molecular surveillance from a tertiary care hospital. [PDF]
Gupta S +12 more
europepmc +1 more source

