Results 241 to 250 of about 34,432,607 (299)

Hypoxia‐Induced ADAM23 Drives Neuron–Tumor Crosstalk and Therapeutic Resistance in Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Hypoxia and nutrient deprivation are fundamental drivers of tumor aggressiveness and therapeutic resistance in hepatocellular carcinoma (HCC). While the involvement of neural components in the tumor microenvironment (TME) is increasingly recognized, the molecular transducers linking metabolic stress to neuron–tumor crosstalk remain elusive ...
Taehyun Park, Soeun Kim, Hyunjung Cho, Johyeon Nam, Dayoung Choi, Misu Lee   +5 more
wiley   +1 more source

Probable Tizanidine-Induced Acute Liver Failure Requiring Liver Transplantation. [PDF]

ACG Case Rep J
Anwar O, Shah M, Yan L, Torres D.
europepmc   +1 more source

Precision immunomodulation for pediatric hemophagocytic lymphohistiocytosis in intensive care

Pediatric Investigation, EarlyView.
This review presents a bedside framework for recognizing pediatric hemophagocytic lymphohistiocytosis and cytokine storm, stabilizing organ dysfunction, identifying the underlying phenotype, selecting targeted immunomodulation, considering extracorporeal adjuncts, and reassessing response within 24–72 h. ABSTRACT Hemophagocytic lymphohistiocytosis (HLH)
Weerapong Lilitwat, Prakreeti Bhandari
wiley   +1 more source

Intra-host viral population dynamics during acute hepatitis E virus infection. [PDF]

mBio
Janshoff S, Plümers R, Kohl A, Nocke MK, Behrendt P, Knabbe C, Costa R, Vollmer T, Todt D, Steinmann E, Gömer A.   +10 more
europepmc   +1 more source

Diagnosis of Portal Hypertension: Advancing Towards Non‐Invasive Solutions

Portal Hypertension &Cirrhosis, EarlyView.
This review systematically summarizes a full spectrum of non‐invasive diagnostic approaches for portal hypertension (PH), including imaging modalities, elastography, serum biomarkers, composite scoring systems and endoscopic ultrasound‐guided portal pressure gradient (EUS‐PPG), and analyzes their performance across different liver disease etiologies ...
Lijia Yin, Huikuan Chu, Ling Yang
wiley   +1 more source

Acute Severe Autoimmune Hepatitis Presenting as Acute-on-Chronic Liver Failure Requiring Urgent Liver Transplantation: A Case Report. [PDF]

Cureus
Pereira da Silva T, De Sá AC, Ferreira AL, Freitas S, Alves G.   +4 more
europepmc   +1 more source

Epigenetic Regulation of Liver Fibrosis: Mechanisms and Therapeutic Implications

Portal Hypertension &Cirrhosis, EarlyView.
This review synthesizes the epigenetic mechanisms—DNA methylation, histone modifications, and non‐coding RNAs—that drive hepatic stellate cell activation and the progression of liver fibrosis. It further evaluates emerging therapeutic strategies targeting these epigenetic regulators, including DNA methyltransferase and histone deacetylase inhibitors ...
Maryam Jadid Tavaf, Mahboobeh Ebrahimi Varkiani, Saeid Abroun, Pedram Asadi‐Sarabi, Shukoofeh Torabi, Elham Rismani, Mohammad Majd Hammour, Andreas K. Nüssler, Massoud Vosough   +8 more
wiley   +1 more source

Hepatitis E Virus Infection in Pregnant Women. [PDF]

Microorganisms
Wang Z, Ge YS, Wang MM, Zhou YL, Wen GP.
europepmc   +1 more source

Skeletal Muscle Mass Improvement and Survival After TIPS in Patients With Cirrhosis and Low Skeletal Muscle Index

Portal Hypertension &Cirrhosis, EarlyView.
Sarcopenia is common in patients with cirrhosis and contributes to poor prognosis. This study investigated whether transjugular intrahepatic portosystemic shunt (TIPS) is associated with improvement in skeletal muscle mass and whether such improvement translates into better transplant‐free survival in patients with cirrhosis and low skeletal muscle ...
Qinnian Li, Jiamin Xu, Chenrui Zhang, Rongfang Tu, Weimin Bao, Yingmei Tang   +5 more
wiley   +1 more source