Results 101 to 110 of about 24,285 (335)

Increased missense mutation burden of Fatty Acid metabolism related genes in nunavik inuit population. [PDF]

open access: yesPLoS ONE, 2015
Nunavik Inuit (northern Quebec, Canada) reside along the arctic coastline where for generations their daily energy intake has mainly been derived from animal fat.
Sirui Zhou   +11 more
doaj   +1 more source

Electron transport phosphorylation in rumen butyrivibrios: unprecedented ATP yield for glucose fermentation to butyrate. [PDF]

open access: yes, 2015
From a genomic analysis of rumen butyrivibrios (Butyrivibrio and Pseudobutyrivibrio sp.), we have re-evaluated the contribution of electron transport phosphorylation (ETP) to ATP formation in this group.
Firkins, Jeffrey L, Hackmann, Timothy J
core   +2 more sources

Molecular species of phosphatidylcholine in abetalipoproteinemia: effect of lecithin:cholesterol acyltransferase and lysolecithin acyltransferase.

open access: yesJournal of Lipid Research, 1989
In order to study the role of very low density lipoproteins (VLDL) and low density lipoproteins (LDL) in determining the molecular species composition of phosphatidylcholine (PC) and the specificity of lecithin:cholesterol acyltransferase (LCAT) in human plasma, we studied the PC species composition in plasma from abetalipoproteinemic (ABL) and control
R. E. Gregg   +3 more
openaire   +4 more sources

Erucic Acid, Derived by Lactobacillus Crispatus, Induces Ferroptosis in Cervical Cancer Organoids Through the PPAR‐δ Signaling Pathway

open access: yesAdvanced Science, EarlyView.
Utilizing PDO, cell lines and cervical cancer xenograft (CDX) models, the study demonstrate both in vitro and in vivo that the metabolite of L. crispatus, erucic acid, can modulate the proliferation, migration and invasion of cervical cancer by activating the PPAR‐δ pathway.
Qianwei Zhen   +8 more
wiley   +1 more source

The plasma lecithin:cholesterol acyltransferase reaction

open access: yesJournal of Lipid Research, 1968
Evidence for the existence of a plasma lecithin : cholesterol acyltransferase is reviewed with emphasis not only on the lipid reactants, but also on the lipoprotein "substrates" and "products." The cholesteryl esters of all major lipoprotein classes become labeled when plasma is incubated with cholesterol-(14)C. However, the smaller, lecithin-rich high
openaire   +4 more sources

Bimetallic Nanozyme Amplifier for Synergistic Ferroptosis‐Cuproptosis and Metabolic Reprogramming to Reshape Immunosuppressive Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
The Bimetallic Nanozyme Amplifier (PEG@AuCZ@CC) to maximize hydrogen peroxide production and reprogram tumor metabolism from glycolysis to oxidative phosphorylation. This shift enhances ferroptotic/cuproptotic signaling cascades and creates a glucose‐enriched but lactate‐depleted tumor microenvironment (TME), effectively overcoming immune tolerance in ...
Jianzhang Luo   +9 more
wiley   +1 more source

Cocoa butter-like lipid production ability of non-oleaginous and oleaginous yeasts under nitrogen-limited culture conditions [PDF]

open access: yes, 2017
Cocoa butter (CB) extracted from cocoa beans is the main raw material for chocolate production. However, growing chocolate demands and limited CB production has resulted in a shortage of CB supply.
Nielsen, Jens   +2 more
core   +2 more sources

Metabolism of polyunsaturated fatty acids in human bone marrow derived mesenchymal stromal cells [PDF]

open access: yes, 2017
The application of human bone marrow derived mesenchymal stromal cells (hBMSCs) for regenerative or immunomodulatory therapies, e.g. treatment of the graft-versus-host disease, requires in vitro expansion of the cells.
Tigistu-Sahle, Feven
core  

MBOAT7 rs641738 increases risk of liver inflammation and transition to fibrosis in chronic hepatitis C [PDF]

open access: yes, 2016
Cirrhosis likely shares common pathophysiological pathways despite arising from a variety of liver diseases. A recent GWAS identified rs641738, a polymorphism in the MBOAT7 locus, as being associated with the development of alcoholic cirrhosis.
Abate, Maria Lorena   +40 more
core   +5 more sources

Radiation inactivation analysis of acyl-CoA:retinol acyltransferase and lecithin:retinol acyltransferase in rat liver

open access: yesJournal of Lipid Research, 1993
Microsomes from liver and several other tissues esterify retinol through both fatty acyl-CoA-dependent and -independent reactions. Two activities, acyl-CoA:retinol acyltransferase (ARAT) and lecithin:retinol acyltransferase (LRAT) activities, have been characterized enzymatically but neither has yet been purified and characterized biochemically.
A C Ross, E S Kempner
openaire   +4 more sources

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