Results 81 to 90 of about 2,318 (247)

Control of lecithin biosynthesis in erythrocyte membranes

open access: yesJournal of Lipid Research, 1968
The detailed relationship between the relative composition of the potential precursor acids, the esterification rates of their CoA thiol ester derivatives, and the relative composition of the fatty acids in the product, lecithin, which was isolated from ...
Keizo Waku, W.E.M. Lands
doaj   +1 more source

The zDHHC family of S-acyltransferases [PDF]

open access: yesBiochemical Society Transactions, 2015
The discovery of the zDHHC family of S-acyltransferase enzymes has been one of the major breakthroughs in the S-acylation field. Now, more than a decade since their discovery, major questions centre on profiling the substrates of individual zDHHC enzymes (there are 24 ZDHHC genes and several hundred S-acylated proteins), defining the mechanisms of ...
Lemonidis, Kimon   +7 more
openaire   +4 more sources

Palmitoyl Acyltransferase Zdhhc17 Promotes Functional Recovery After Spinal Cord Injury by Targeting the Nuclear Transport Factors Kpna2 and Ipo9

open access: yesAdvanced Science, EarlyView.
In this study, we demonstrate that Zdhhc17, acting as a PAT, suppresses neuronal apoptosis and promotes axon regeneration after injury, thereby enhancing functional recovery following SCI. In this context, Kpna2 and Ipo9 serve as novel palmitoylation substrates of Zdhhc17, whose palmitoylation prevents the injury‐induced degradation of their proteins ...
Meixuan Chen   +12 more
wiley   +1 more source

Recent progress on acyl CoA: lysophospholipid acyltransferase research

open access: yesJournal of Lipid Research, 2009
Cells of all organisms are enclosed by a plasma membrane containing bipolar lipids, cholesterol, and proteins. Cellular membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in cells ...
Hideo Shindou   +4 more
doaj   +1 more source

Aspirin‐Derived Salicyl‐CoA Drives Histone Lysine Salicylation Regulated by CBP and SIRT2

open access: yesAdvanced Science, EarlyView.
Aspirin‐derived salicyl‐CoA serves as a previously unrecognized acyl donor for protein lysine salicylation. This study identifies histone lysine salicylation as a reversible epigenetic modification regulated by CBP and SIRT2, expanding the biochemical actions of aspirin beyond its canonical acetylation‐dependent mechanisms and providing a new framework
Facai Zhang   +15 more
wiley   +1 more source

Increased missense mutation burden of Fatty Acid metabolism related genes in nunavik inuit population. [PDF]

open access: yesPLoS ONE, 2015
Nunavik Inuit (northern Quebec, Canada) reside along the arctic coastline where for generations their daily energy intake has mainly been derived from animal fat.
Sirui Zhou   +11 more
doaj   +1 more source

Improving the Physicochemical Properties, Organic Acids, Amino Acids, Volatile Organic Compounds, and Metabolites of Laohan Melon Juice Through Fermentation With Different Lactic Acid Bacteria

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
Fermentation with lactic acid bacteria could improve amino acids, volatile organic compounds (VOCs), and nonvolatile metabolites of Laohan melon juice (LMJ), which provides theoretical guidance for the development of Laohan melon beverage and advances knowledge of the metabolic mechanisms of VOCs in LMJ.
Yun Xie   +12 more
wiley   +1 more source

The microsomal cardiolipin remodeling enzyme acyl-CoA lysocardiolipin acyltransferase is an acyltransferase of multiple anionic lysophospholipids

open access: yesJournal of Lipid Research, 2009
Phospholipids are subjected to remodeling through the Lands cycle to attain appropriate FA compositions. In recent years, at least two families of lysophospholipid acyltransferases have been identified. Acyl-CoA lysocardiolipin acyltransferase 1 (ALCAT1)
Yang Zhao   +4 more
doaj   +1 more source

Acyltransferases in plants: a good time to be BAHD

open access: yes, 2006
Acylation is a common and biochemically significant modification of plant secondary metabolites. Plant BAHD acyltransferases constitute a large family of acyl CoA-utilizing enzymes whose products include small volatile esters, modified anthocyanins ...
D'Auria, J., D'Auria, John
core   +1 more source

Functional characterization of acyltransferases from Salvia hispanica that can selectively catalyze the formation of trilinolenin

open access: yes, 2021
Gopalam, Rahul, Tumaney, Ajay W. (2021): Functional characterization of acyltransferases from Salvia hispanica that can selectively catalyze the formation of trilinolenin. Phytochemistry (112712) 186: 1-9, DOI: 10.1016/j.phytochem.2021.112712, URL: http:/
Gopalam, Rahul, Tumaney, Ajay W.
core   +1 more source

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