Complete replacement of Arabidopsis oil-producing enzymes with heterologous diacylglycerol acyltransferases. [PDF]
McGuire ST +4 more
europepmc +1 more source
Impaired Adipose Anabolism in Pancreatic Cancer Cachexia Is Reversed by HuR Inhibition
ABSTRACT Background Cachexia is defined by chronic loss of fat and muscle, is a frequent complication of pancreatic ductal adenocarcinoma (PDAC) and negatively impacts patient outcomes. Nutritional supplementation cannot fully reverse tissue wasting, and the mechanisms underlying this phenotype are unclear.
Paige C. Arneson‐Wissink +10 more
wiley +1 more source
Carnitine O-Acetyltransferase as a Central Player in Lipid and Branched-Chain Amino Acid Metabolism, Epigenetics, Cell Plasticity, and Organelle Function. [PDF]
Volpicella M +7 more
europepmc +1 more source
ABSTRACT Metabolic dysfunction‐associated fatty liver disease (MAFLD), recently redefined from non‐alcoholic fatty liver disease (NAFLD), highlights the central role of metabolic dysfunction in its pathophysiology. The L‐α‐lysophosphatidylinositol/G protein‐coupled receptor 55 (LPI/GPR55) axis, an element of the endocannabinoidome, has emerged as a key
Jerome Lian +3 more
wiley +1 more source
Biochemical Properties and Substrate Specificity of Two Acyl-CoA:Lysophosphatidic Acid Acyltransferases (<i>Pt</i>ATS2a and <i>Pt</i>ATS2b) from Diatom <i>Phaeodactylum tricornutum</i>. [PDF]
Jasieniecka-Gazarkiewicz K +3 more
europepmc +1 more source
Effects of Cannabidiol on TAFAZZIN‐Deficient B‐Lymphoblastoid Cells
Deficiency of the cardiolipin remodeling enzyme TAFAZZIN causes Barth syndrome (BTHS), resulting in cardiolipin loss, monolysocardiolipin (MLCL) accumulation, and electron transport chain (ETC) abnormalities in B‐lymphoblastoid cells. Effects of the non‐psychotropic phytocannabinoid cannabidiol (CBD) were examined on B‐lymphoblastoid cells from ...
John Z. Chan +10 more
wiley +1 more source
Recent Progress in <i>N</i>-Acylethanolamine Research: Biological Functions and Metabolism Regulated by Two Distinct <i>N</i>-Acyltransferases: cPLA<sub>2</sub>ε and PLAAT Enzymes. [PDF]
Uyama T +3 more
europepmc +1 more source
Physiological and biochemical effects of different expression of acyl-CoA: lysophosphatidylethanolamine acyltransferases encoding genes observed in arabidopsis plants cultivated under low and standard temperatures. [PDF]
Jasieniecka-Gazarkiewicz K +2 more
europepmc +1 more source

