Results 161 to 170 of about 12,733 (207)

A review on lecithin:cholesterol acyltransferase deficiency

Clinical Biochemistry, 2015
Lecithin cholesterol acyl transferase (LCAT) is a plasma enzyme which esterifies cholesterol, and plays a key role in the metabolism of high-density lipoprotein cholesterol (HDL-C). Genetic disorders of LCAT are associated with lipoprotein abnormalities including low levels of HDL-C and presence of lipoprotein X, and clinical features mainly corneal ...
Ramesh, Saeedi, Min, Li, Jiri, Frohlich
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Purification and Characterization of Lecithin:Cholesterol Acyltransferase

Scandinavian Journal of Clinical and Laboratory Investigation, 1978
The purification of lecithin:cholesterol acyltransferase (LCAT] from human plasma is reported. Hydroxylapatite fractions were approximately 16,000 fold purified over the starting plasma and were free of high-density lipoprotein (HDL) and albumin.
E, Gustow, K G, Varma, L A, Soloff
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Lysophospholipid acyltransferases

Current Opinion in Lipidology, 2012
Over the past several years, many more isoforms for the same enzymes, specifically for 1-acylglycerol-3-phosphate O-acyltransferases (AGPATs), have been cloned and studied. In this review, we summarize their biochemical features and discuss their functional role.The most significant role of these AGPATs appeared from our observation of AGPAT2 in the ...
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Structure and Function of Carnitine Acyltransferases

Annals of the New York Academy of Sciences, 2004
Abstract: Carnitine acyltransferases catalyze the exchange of acyl groups between carnitine and coenzyme A (CoA). These enzymes include carnitine acetyltransferase (CrAT), carnitine octanoyltransferase (CrOT), and carnitine palmitoyltransferases (CPTs).
Gerwald, Jogl, Yu-Shan, Hsiao, Liang, Tong   +2 more
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A protein cofactor of lecithin:Cholesterol acyltransferase

Biochemical and Biophysical Research Communications, 1972
Abstract The effect of proteins isolated from human high density lipoprotein on cholesterol esterification by purified lecithin:cholesterol acyltransferase in the presence of dispersed lipids was studied. One of the major proteins present gave a maximal rate of esterification similar to that found with the native lipoprotein.
C J, Fielding, V G, Shore, P E, Fielding
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Mammalian acyl-CoA:cholesterol acyltransferases

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2000
Cholesterol, the chief sterol found in vertebrates, exists both as a free sterol and as a component of cholesterol esters, which are synthesized by acyl-CoA:cholesterol acyltransferase (ACAT) enzymes. Considerable knowledge concerning cholesterol ester metabolism has accumulated during the past century. However, rapid advances have occurred in the past
K F, Buhman, M, Accad, R V, Farese
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Glycerolipid acyltransferases from rat liver: 1-acylglycerophosphate acyltransferase, 1-acylglycerophosphorylcholine acyltransferase, and diacylglycerol acyltransferase.

Methods in enzymology, 1981
S, Yamashita, K, Hosaka, Y, Miki, S, Numa   +3 more
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Lecithin:retinol acyltransferase in ARPE-19

Experimental Eye Research, 2005
The purpose of this study is to investigate if a readily available cell line (APRE-19) may be used to study in vitro function of visual cycle enzymes such as lecithin:retinol acyltransferase (LRAT). Cells incubated with exogenous retinol accumulated intracellular all-trans retinol and all-trans retinyl ester.
Simon G, Trevino, Steven T, Schuschereba, Phillip D, Bowman, Andrew, Tsin   +3 more
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Inhibition of acyltransferase in lymphocytes by concanavalin A

Biochimica et Biophysica Acta (BBA) - General Subjects, 1980
The effects of concanavalin A and succinylated concanavalin A on the transformation of mouse splenic lymphocytes, and on early biochemical events in the transformation, were compared. 1. The transformation of lymphocytes is biphasic with respect to concanavalin A concentration with optimal activation at about 1 microgram/ml.
P, Dobson, A, Mellors
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Acyltransferases and Triacylglycerols

2018
Glycerolipids, by far the largest group of plant lipids, are structurally based on glycerol. This group includes glycodiacylglycerols, phospholipids, and acylglycerols such as triacylglycerol. The properties of the triacylglycerols depend on the fatty acids esterified with each of the three hydroxyl groups of glycerol.
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