Results 161 to 170 of about 11,126 (242)

Lecithin-Cholesterin-Acyltransferase [PDF]

, 2018
K. J. Lackner, D. Peetz
openaire   +1 more source

Elucidating the Causal Relationships Between B Cells, Dendritic Cells, and Multiple Sclerosis Pathogenesis

Brain and Behavior, Volume 16, Issue 3, March 2026.
This study presents an integrative pipeline linking immune cell traits to multiple sclerosis (MS) susceptibility. Genome‐wide association and Mendelian randomization analyses revealed causal roles of immune cells in MS risk. Colocalization and pleiotropy mapping identified candidate genes, further refined through functional annotation, network analysis,
Xuefei Wang, Yangwei Wang, Xiaojing Liu
wiley   +1 more source

The multifaceted roles of the ACSL family in cancer: Metabolic reprogramming, ferroptosis regulation and tumour immune microenvironment remodelling

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
The acyl‐CoA synthetase long‐chain (ACSL) family consists of five members, which exhibit a synergistic effect in promoting tumour lipid metabolism for energy supply. Specifically, ACSL3 and ACSL4 have antagonistic effects on the mechanisms related to ferroptosis in tumour cells.
Haocai Li, Weijian Wang, Juncheng Zhan, Yuxiang Xiao, Xiaoping Chen, Chen Su, Peng Zhu   +6 more
wiley   +1 more source

Integrated metabolomic and transcriptomic analysis of <i>Pogostemon cablin</i> shed new light on the complete biosynthesis pathway of pogostone. [PDF]

Front Plant Sci
Wang S, Zeng Z, Zhang Q, Liu W, Liu Q, Xie C, Bei J, Chen B, Zhang A.   +8 more
europepmc   +1 more source

Ninjurin1 in cardiovascular and vascular biology: From molecular mechanisms to therapeutic opportunities

Clinical and Translational Medicine, Volume 16, Issue 3, March 2026.
NINJ1 mediates PMR in cardiovascular cell death, releasing DAMPs that amplify vascular inflammation. Dual NINJ1 paradox: membrane‐bound form drives endothelial NF‐κB/CXCL‐8 inflammation while soluble form provides atheroprotection. Pericyte NINJ1 regulates the critical balance between angiogenic sprouting and vessel maturation in ischaemic tissues ...
Muhammad Mamunur Rashid Mahib
wiley   +1 more source

A Zdhhc22-mCherry BAC transgenic mouse line reveals neuronal expression dynamics in the developing and adult CNS. [PDF]

Brain Struct Funct
Yang H, Ryu J, Choi JW, Nam KH, Byun HJ, Jang SW, Shim S.   +6 more
europepmc   +1 more source

Evaluation of Urine Exosome Lecithin Cholesterol Acyltransferase as a Biomarker for Diabetes Diagnosis and Dyslipidemia

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 3, March 2026.
Integrated proteomic and model studies reveal lipid metabolism dysregulation in diabetes, detectable even in prediabetes. LCAT, a key regulator, shows compensatory upregulation during progression. The characteristic dynamics of urine exosome LCAT provide a basis for its use as a non‐invasive biomarker for early diabetic detection and disease monitoring.
Tianci Liu, Na Liu, Qian Meng, Tao Li, Man Zhang   +4 more
wiley   +1 more source

Identification and functional characterization of BAHD acyltransferases associated with anthocyanin acylation in blueberry. [PDF]

Hortic Res
Mengist MF, Abid MA, Grace MH, Seth R, Bassil N, Kay CD, Dare AP, Chagné D, Espley RV, Neilson A, Lila MA, Ferruzzi M, Iorizzo M.   +12 more
europepmc   +1 more source

Lysocardiolipin Acyltransferase 1 [PDF]

, 2020
openaire   +1 more source

Phloretin Suppresses Preadipocyte Differentiation by Targeting PPARγ/Transferrin to Activate Ferroptosis Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
Phloretin alleviates HFD‐induced obesity and suppresses adipogenesis by activating the ferroptosis pathway, potentially via targeting PPARγ and transferrin. ABSTRACT Phloretin, a plant‐derived dihydrochalcone bioactive compound, potentially modulates preadipocyte differentiation, although this remains controversial and requires further clarification ...
Jie Li, Qihui Zhu, Yang Li, Haiyu Zhao, Yi Bi, Chuanying Pan, Min Wang, Lin Han, Xianyong Lan   +8 more
wiley   +1 more source