Results 181 to 190 of about 24,285 (335)

Sex‐ and APOE Genotype–Dependent Pain Susceptibility and Alzheimer's Risk Mediated by the Lipid Metabolism Enzyme LPCAT2

Aging Cell, EarlyView.
We aimed to uncover the molecular mechanisms linking age‐related pain susceptibility with cognitive decline in Alzheimer's disease (AD). By integrating transcriptomic, human AD brain, genomic, and Mendelian randomization analyses, we identified the lipid‐modifying enzyme LPCAT2 as a sex‐ and APOE genotype–dependent causal mediator of both heightened ...
Rai‐Hua Lai, Ren‐Hua Chung, Wan‐Yu Pai, Yi‐Chung Chen, Ka‐Hei Lam, Cheng‐Nong Lai, Jyh‐Lyh Juang   +6 more
wiley   +1 more source

Subcellular localization of acyl coenzyme A: dihydroxyacetone phosphate acyltransferase in rat liver peroxisomes (microbodies).

, 1979
A K Hajra, Caryl Burke, Christopher L. Jones   +2 more
openalex   +1 more source

Effect of Essential Amino Acid Deficiency on Lecithin - Cholesterol Acyltransferase in Rat Plasma : Dietary Factors Influencing Lecithin - Cholestetol Acyltransferase in Rat Plasma (Part 3) [PDF]

, 1974
Kohji Hori, Shuji Fujita, Kuo-Yu Ho, Michihiro Sugano   +3 more
openalex   +1 more source

Identification of BAHD-acyltransferase enzymes involved in ingenane diterpenoid biosynthesis. [PDF]

New Phytol
Schotte C, Florean M, Czechowski T, Gilday A, Alam RM, Ploss K, Wurlitzer J, Li Y, Sonawane P, Graham IA, O'Connor SE.   +10 more
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Editorial: In-depth interpretation of critical genomic information related to the biosynthesis of key specialized (secondary) metabolism in medicinal plants. [PDF]

Front Plant Sci
Wang M, Guo X, Wang Z.
europepmc   +1 more source

CTCF Is Essential for the Development and Maintenance of CALM‐AF10‐Induced Leukemia

Cancer Science, EarlyView.
CTCF regulates TGM2 gene expression by modulating key histone modifications, including increased acetylation of H3K27 (H3K27ac) and trimethylation of H3K4 (H3K4me3), along with decreased trimethylation of H3K27 (H3K27me3). These epigenetic changes are critical for maintaining the stem‐like properties of CALM‐AF10‐induced AML. Pharmacological inhibition
Yoko Kuroki, Kazutsune Yamagata, Yukiko Aikawa, Yutaka Shima, Hisafumi Shioneri, Issay Kitabayashi   +5 more
wiley   +1 more source

Multifunctional acyltransferases involved in the synthesis of triacylglycerol, fatty acid phytyl esters and plastoquinol esters in cyanobacteria. [PDF]

Planta
Shajil Das A, Shajil Das A, Chen Z, Peisker H, Gutbrod K, Hölzl G, Dörmann P.   +6 more
europepmc   +1 more source

Six New Cases of 22q13.2 Gain Including TFC20: First Report of Triplication and Smallest Duplication Associated With Neurodevelopmental Delays

Clinical Genetics, EarlyView.
This study reports six new cases of 22q13.2 duplication and triplication, including the TCF20 gene, associated with neurodevelopmental disorders and various morphological and systemic abnormalities. The findings suggest a variable expressivity, but their complete penetrance remains uncertain compared to well‐established loss‐of‐function variants ...
Etienne Bizot, Dima Jouni, Caroline Rooryck, Juliet Taylor, Marine Legendre, Lorelei Charbonnier, Julia Metreau, Emmanuelle Benaloun, Audrey Pinson, Geneviève Quenum, Jérôme Bouligand, Gérard Tachdjian, Philippe Labrune, Lucie Tosca   +13 more
wiley   +1 more source

Triacylglycerol synthesis in isolated fat cells. Studies on the microsomal diacylglycerol acyltransferase activity using ethanol-dispersed diacylglycerols.

, 1976
Rosalind Coleman, Robert M. Bell
openalex   +1 more source