Toward molecular phenotyping of temporal lobe epilepsy by spatial omics
Abstract Objective In temporal lobe epilepsy (TLE), detection of the epileptogenic zone predicts a good surgical outcome. When submitted to 18F‐fluorodeoxyglucose positron emission tomography (PET), some patients display lateralized, focal hypometabolism in the temporal lobe (PET+), whereas others appear normometabolic (PET−).
Isabeau Vermeulen+33 more
wiley +1 more source
Identification and functional characterization of BAHD acyltransferases associated with anthocyanin acylation in blueberry. [PDF]
Mengist MF+12 more
europepmc +1 more source
MBOAT7 encephalopathy: Characterizing the neurology and epileptology
Abstract Objective Biallelic pathogenic MBOAT7 variants are associated with neurodevelopmental disorders, intellectual disability (ID), epilepsy, and neuropsychiatric disorders such as attention‐deficit/hyperactivity disorder and autism spectrum disorders. We aimed to characterize the epilepsy phenotype in a cohort of patients affected by this syndrome.
Sebastian Ortiz De la Rosa+28 more
wiley +1 more source
Acyl-CoA: lysophosphatidylcholine acyltransferase from diatom P. Tricornutum efficiently remodels phosphatidylcholine containing polyunsaturated fatty acids. [PDF]
Jasieniecka-Gazarkiewicz K+3 more
europepmc +1 more source
Two Acyltransferases Contribute Differently to Linolenic Acid Levels in Seed Oil1[OPEN]
Sofia Marmon+5 more
semanticscholar +1 more source
Pathological significance of intranuclear structures in liver biopsy samples
Schematic representation of the potential significance of three distinct nuclear structures. Glycogenated nuclei reflects excessive glycogen accumulation in the hepatocytes. Nucleoplasmic lipid droplets form in the nucleus during hepatocyte injury. Cytoplasmic lipid droplets in the nucleoplasmic reticulum are suppressed when there is excessive fat ...
Norihiro Imai+15 more
wiley +1 more source
Integrated metabolite profiling and transcriptome analysis identify candidate genes involved in diterpenoid alkaloid biosynthesis in <i>Aconitum pendulum</i>. [PDF]
Wang T+8 more
europepmc +1 more source
In metabolic dysfunction‐associated steatotic liver disease/metabolic dysfunction‐associated steatohepatitis patients aged <60 years, high serum β‐cryptoxanthin concentrations were inversely associated with CVD mortality. Abstract Aim High cardiovascular disease (CVD) mortality occurred among metabolic dysfunction‐associated steatotic liver disease ...
Qian‐Qian Wang+5 more
wiley +1 more source
Heterogeneity of human high density lipoprotein: Presence of lipoproteins with and without apoE and their roles as substrates for lecithin:cholesterol acyltransferase reaction [PDF]
Yves L. Marcel+3 more
openalex +1 more source