Results 211 to 220 of about 17,541 (293)

Bone Metastasis: Molecular Mechanisms, Clinical Management, and Therapeutic Targets

MedComm, Volume 7, Issue 2, February 2026.
This figure emphasizes current understanding of the regulatory networks, approach of diagnose, available preclinical models and clinical management of bone metastasis. to guide future therapeutic development. A deep understanding of these aspects enables the prevention of bone metastasis and the implementation of effective therapeutic strategies ...
Jingyuan Wen, Binghua Li, Shengjia Wang, Yongzhong Yao, Zhao Huang, Decai Yu   +5 more
wiley   +1 more source

Protein S-Palmitoylation as Potential Therapeutic Target for Dermatoses. [PDF]

Biomolecules
Feng Y, Wu J, Tang H, Liu S, Jia H, Liang Y, Li Z, Li L, Li L, Lei X.   +9 more
europepmc   +1 more source

Influence of vesicle surface composition on the interfacial binding of lecithin:cholesterol acyltransferase and apolipoprotein A-I

, 1997
K.R. Miller, John S. Parks
openalex   +1 more source

Diversity of FAAL enzymes and prediction of their substrate specificity using FAALPred

Protein Science, Volume 35, Issue 2, February 2026.
Abstract FAALs (fatty acyl‐AMP ligases) recruit and incorporate fatty acids during the biosynthesis of secondary metabolites. Their diversity, distribution, and substrate specificity remain poorly understood, which limits functional predictions from sequence data.
Anne Liong, Leandro de Mattos Pereira, Pedro N. Leão   +2 more
wiley   +1 more source

A Lipidomic Analysis Reveals Dynamic Changes of Polar Lipids for Oil Biosynthesis During Cotyledon Development in <i>Perilla frutescens</i>. [PDF]

Plants (Basel)
Liu X, Zhang J, Xu W, Du X, Yang D, Xu L, Zhang S, Gao T.   +7 more
europepmc   +1 more source

Early activation of hepatic stellate cells induces rapid initiation of retinyl ester breakdown while maintaining lecithin:retinol acyltransferase (LRAT) activity

Maya W. Haaker, Vera Goossens, Nina A.N. Hoogland, H. van Doorne, Ziqiong Wang, Jeroen W. A. Jansen, Dora V. Kaloyanova, Chris H.A. van de Lest, Martin Houweling, Arie B. Vaandrager, J. Bernd Helms   +10 more
openalex   +1 more source

Lysocardiolipin Acyltransferase 1 [PDF]

, 2020
openaire   +1 more source

Role of the transmembrane domain in severe acute respiratory syndrome (SARS) coronavirus 2 spike for palmitoylation and membrane fusion

Protein Science, Volume 35, Issue 2, February 2026.
Abstract Palmitoylation is a reversible post‐translational modification that enhances protein hydrophobicity and regulates cellular functions such as trafficking and signaling. In humans, this modification is catalyzed by 23 DHHC enzymes, but the mechanisms by which they recognize their substrates remain unclear.
Dina A. Abdulrahman, Michael Veit
wiley   +1 more source

A Metabolomics and Transcriptomics Resource for Identifying Candidate Genes in the Biosynthesis of Specialised Metabolites in Populus tremula. [PDF]

Physiol Plant
Rydman SM, Lihavainen J, Robinson KM, Jansson S, Albrectsen BR, Street NR.   +5 more
europepmc   +1 more source

The Crystal Structure of Human Transport and Golgi Organization 2 Homolog (TANGO2) Protein Reveals an αββα‐Fold Arrangement

Proteins: Structure, Function, and Bioinformatics, Volume 94, Issue 2, Page 515-528, February 2026.
ABSTRACT Transport and Golgi Organization 2 Homolog (TANGO2) protein deficiency disorder (TDD) is a rare autosomal recessive disorder characterized by multi‐systemic abnormalities and significant phenotypic variability including neurodevelopmental delay, seizures, intermittent ataxia, hypothyroidism, rhabdomyolysis, life‐threatening metabolic ...
Anne Cooper, Alyssa Powers, Kevin P. Battaile, Al‐Walid Mohsen, David K. Johnson, Scott Lovell, Lina Ghaloul‐Gonzalez   +6 more
wiley   +1 more source