Editorial: In-depth interpretation of critical genomic information related to the biosynthesis of key specialized (secondary) metabolism in medicinal plants. [PDF]
Wang M, Guo X, Wang Z.
europepmc +1 more source
Root hair plasticity in cereals under abiotic stress
An integrative perspective on how to study the regulation of root hair plasticity to increase the resilience of cereals to abiotic stress. Summary Abiotic stress is a constant threat to crop growth and yield in the context of climate change. Root systems that can best adapt their architecture to environmental challenges contribute to enhanced ...
Yaping Zhou, Frank Hochholdinger
wiley +1 more source
Bioorthogonal Click Chemistry for Antibody-Free Profiling of Acetylation, Propionylation, and Butyrylation in <i>Pseudomonas aeruginosa</i> and Methicillin-Resistant <i>Staphylococcus aureus</i>. [PDF]
Monacchio HN +5 more
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Mutasynthesis and Antibiotic Activity of Mupirocin Analogues
A mutasynthetic strategy was developed to prepare pseudomonic acid analogues, and their antimicrobial activities were evaluated against five bacterial strains. Feeding studies with mutant strains of Pseudomonas fluorescens revealed that C7‐desepoxy‐PA‐B was metabolised to C7‐PA‐C with loss of the 8‐hydroxyl group, but no fatty acid chain extension ...
Sarah M. Husain +11 more
wiley +1 more source
Dissection and Engineering of Modular Polyketide Synthase Extender Unit Specificity Motifs
Motif‐level engineering of acyltransferase domains in polyketide synthases enables programable extender unit selectivity. Cooperative mutations and motif exchanges reprogram substrate preference, enabling the incorporation of non‐native extender units and expanding polyketide structural diversity, with gains in activity and product yield.
Sydney Welch, Gavin J. Williams
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Energetic stress in combination with impaired fatty acid oxidation induces sequestration of CoA and adaptation of CoA metabolism. [PDF]
Kiyuna LA +17 more
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Multifunctional acyltransferases involved in the synthesis of triacylglycerol, fatty acid phytyl esters and plastoquinol esters in cyanobacteria. [PDF]
Shajil Das A +6 more
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Regulation of Cholesterol and Triglyceride Metabolism by Fatty acid Ethanolamides. [PDF]
Davies SS, Fadaei R.
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Carnitine O-Acetyltransferase as a Central Player in Lipid and Branched-Chain Amino Acid Metabolism, Epigenetics, Cell Plasticity, and Organelle Function. [PDF]
Volpicella M +7 more
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Analysis of ligand recognition by choline O-acetyltransferase reveals thiol-reactive assay interference and weak ligand affinity in solution. [PDF]
Forsgren N +9 more
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