Results 41 to 50 of about 4,112,148 (285)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Mobile ad-hoc networks: MANET [PDF]

open access: yesTrendovi u Poslovanju, 2018
Currently in 2018, 7.6 billion people are in the world, and 8.6 billion mobile devices. As mobile phones have completely changed the meaning of the term to be available, a similar change in the wait and laptops users is, so it is only a matter of time ...
Mikarić Bratislav   +2 more
doaj  

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

A Fault and Mobility Tolerant Location Server for Large-scale Ad-hoc networks [PDF]

open access: yes, 2007
There are many essential applications for quorum systems in ad-hoc networks, such as that of location servers in large-scale networks. Existing research proposes many approaches to the problems, many of which are incomplete, cumbersome, or incur ...
Gareth Owen   +3 more
core   +1 more source

A multi-protocol framework for ad-hoc service discovery [PDF]

open access: yes, 2006
Discovering the appropriate services in ad-hoc computing environments where a great number of devices and software components collaborate discreetly and provide numerous services is an important challenge. Service discovery protocols make it possible for
Flores-Cortes, C.   +2 more
core   +3 more sources

Infrastructured ad hoc networks

open access: yesProceedings. International Conference on Parallel Processing Workshop, 2003
In traditional ad hoc networks, all nodes are considered equal and take equal part in the routing and forwarding of packets. We believe that this may not always be desirable. Rather, some nodes may be equipped with virtually unlimited power supplies, while others have to rely on battery power Thus, we propose the creation of "infrastructured" ad hoc ...
Lindgren, Anders, Schelén, Olov
openaire   +3 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Topology-aware multicasting in phased mobile ad hoc networks for e-learning [PDF]

open access: yes, 2012
Includes bibliographical references.This thesis presents an adaptive multicast routing protocol called a Topology-Aware Polymorphic Multicast Routing Protocol (TAPMRP) for use in Mobile Ad hoc NETworks (MANETs).
Chalemba, Leonard Edmond Khaiko
core   +1 more source

IDHOCNET: A Novel ID Centric Architecture for Ad Hoc Networks

open access: yesJournal of Computer Networks and Communications, 2016
Ad hoc networks lack support of infrastructure and operate in a shared bandwidth wireless environment. Presently, such networks have been realized by various adaptations in Internet Protocol (IP) architecture which was developed for infrastructure ...
Shahrukh Khalid   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

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