Results 41 to 50 of about 21,413 (265)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Distinguishability in Entropy Calculations: Chemical Reactions, Conformational and Residual Entropy
Entropy, 2011 By analyzing different examples of practical entropy calculations and using concepts such as conformational and residual entropies, I show herein that experimental calorimetric entropies of single molecules can be theoretically reproduced considering ...
Ernesto Suárez
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Discourse Informativeness in Alzheimer's Disease and Mild Cognitive Impairment
Listy klinicke logopedieIn recent years, the assessment of the language abilities of persons with cognitive deficits has focused on discourse assessment. Specifically, the assessment of informativeness proves to be an effective diagnostic tool.
Viktória Čiernik Kevická +2 more
doaj +1 more source
An Offline Roadside Unit ON-OFF Scheduling Algorithm for Energy Efficiency of Ad Hoc Networks
IEEE Access, 2018 This paper considers the off-line roadside unit (RSU) ON/OFF scheduling problem in a sparse vehicular ad hoc network (VANET). We formulate the problem as a mixed integer non-linear programming problem and propose a heuristic scheduling algorithm called ...
Lei Zhang, Yu Wang
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FEBS Open Bio, EarlyView.We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima +4 more
wiley +1 more source
Ibérica, 2020 This paper examines the role of the adjective “unique” in car manufacturers’ websites. The presence of adjectives is generally acknowledged to be a significant feature of advertising texts; however, analyses often focus on issues relating to the ...
Marisa Díez Arroyo
doaj
E3S Web of Conferences, 2018 After the disastrous flood events of June 2013 in the German Elbe and Danube catchments, the German government together with the federal states decided on the joint elaboration of a nationwide flood protection programme (NHWSP, 2015-2027+).
Schuh Carina, Hatz Marcus
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DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source