Results 71 to 80 of about 21,413 (265)

Real‐World Performance of CSF Kappa Free Light Chains in the 2024 McDonald Criteria

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Kappa free light chains (KFLCs) in the cerebrospinal fluid (CSF) have a similar performance to CSF‐restricted oligoclonal bands (OCB) for multiple sclerosis (MS) diagnosis. To help with implementation, we set out to resolve several remaining uncertainties: (1) performance in a real‐world cohort and the 2024 McDonald criteria; (2 ...
Maya M. Leibowitz   +11 more
wiley   +1 more source

Enhanced DSR Routing Protocol for the Short Time Disconnected MANET [PDF]

open access: yesJournal of Electrical and Electronics Engineering, 2013
Data delivery in Mobile Ad-Hoc network (MANET) is a very difficult task due to the fact the sporadic connections between mobile nodes. For this reason, we introduce the new modified routing protocol that enables the data delivery in the case that the ...
PAPAJ Ján   +2 more
doaj  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende   +26 more
wiley   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher   +10 more
wiley   +1 more source

Incremental steps towards a competency-based post-secondary education system in Ontario

open access: yesTuning Journal for Higher Education, 2014
As one of Canada’s 13 distinct jurisdictions, Ontario is a national leader in developing a competency-based postsecondary education system. Hindered by challenges of a disaggregated system of policy actors in system design, quality assurance and credit ...
Mary Catharine Lennon
doaj   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano   +11 more
wiley   +1 more source

Analyzing sustainable urban development through smart and sustainable cities: an integrated review

open access: yesFrontiers in Sustainable Cities
‘Smart cities’ is an ever-evolving concept focusing on technological integration in urban policymaking to resolve contemporary urban issues. Despite repeated claims that ‘smart initiatives’ produce sustainability, a detailed research analysis is required
Muhammad Farhan Bashir   +4 more
doaj   +1 more source

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati   +10 more
wiley   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Deterministic Prediction of the Entropy Increase in a Sudden Expansion

open access: yesEntropy, 2011
This paper presents the results of a study of the prediction of the entropy growth within an internal free shear layer of an ideal gas flow downstream of a sudden expansion of the flow area. The objective of the study is exploratory in nature by invoking
LaVar King Isaacson
doaj   +1 more source

Home - About - Disclaimer - Privacy