Neurotrophic factor-α1/carboxypeptidase E regulates critical protein networks to rescue neurodegeneration, defective synaptogenesis and impaired autophagy in Alzheimer's disease mice. [PDF]
Transl NeurodegenerXiao L +4 more
europepmc +1 more source
Digital Microneedles for Multiplexed Transdermal Sensing via Fluorescent QR Codes
Advanced Materials, EarlyView.Digital fluorescent microneedles encode biochemical information in skin into scannable QR codes through threshold‐activated probes that generate binary on/off signals. By transforming analog fluorescence into discrete digital patterns, this platform enables calibration‐free, multiplexed transdermal sensing of physiologically relevant biomarkers ...
Farbod Abazar +7 more
wiley +1 more source
Machine-learning-guided transcriptomic integration identifies GFM1 as a lactylation-related candidate biomarker in aortic dissection. [PDF]
Sci RepChen J, Jiang N, Guo Z, Bai Y.
europepmc +1 more source
Advanced Materials Interfaces, EarlyView.Lipid drug carriers to which ultra‐small gold nanoparticles were added enabled more efficient radiotherapy of cultured pancreatic cancer tumors. These nanoparticles boosted radiation‐induced damage to tumors by generating more reactive molecules, though higher gold levels are needed for strong benefits.
Nazareth Milagros Carigga Gutierrez +17 more
wiley +1 more source
Practical Strategies for Integrating Ad Hoc Simulated Participants in Emergency Medicine Education: A Faculty Guide. [PDF]
CureusWong KU, Lei C, Hock SM, Chen TH.
europepmc +1 more source
Advanced Materials Technologies, EarlyView.This study formulated a 5Y‐PSZ zirconia paste for extrusion‐based additive manufacturing via direct ink writing, producing dense ceramic structures for dental applications. A colloidal approach with 47 vol% nanometric powder and tailored additives optimized rheology and printability.
Juliana de Freitas Gouveia Silva +5 more
wiley +1 more source
SYMPHONY: Synergistic Hierarchical Metric-Fusion and Predictive Hybrid Optimization for Network Yield-A VANET Routing Protocol. [PDF]
Sensors (Basel)Kazi AK, Imran M, Asif R, Hina S.
europepmc +1 more source
BLOC: Buildable and Linkable Organ on a Chip
Advanced Materials Technologies, EarlyView.We developed a “Buildable and Linkable Organ on a Chip” (BLOC) that can construct diverse microphysiological systems (MPSs). The BLOC is standardized to the same size and has one of the functions of “Culture,” “Control,” or “Analysis.” Users can freely configure various MPSs, including developing perfusion, cytotoxicity analysis, and biochemical ...
Yusuke Kimura +7 more
wiley +1 more source
Ad hoc bandwidth requests and power conservation in 5G wireless networks with tiny cells. [PDF]
Sci RepRajesh A +6 more
europepmc +1 more source
Advanced Materials Technologies, EarlyView.Transducers convert physical signals into electrical and optical representations, yet each mechanism is bounded by intrinsic trade‐offs across bandwidth, sensitivity, speed, and energy. This review maps transduction mechanisms across physical scale and frequency, showing how heterogeneous integration and multiphysics co‐design transform isolated ...
Aolei Xu +8 more
wiley +1 more source