Results 41 to 50 of about 6,072,971 (285)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Designing a context-aware middleware for asynchronous communication in mobile ad hoc environments [PDF]

, 2004
In mobile ad hoc networks, synchronous communication mechanisms appear to be not suitable, since these assume that the involved entities are present at the same time during the interactions.
Musolesi, Mirco, Musolesi, M., Mirco Musolesi   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Determining design parameters for Ad-hoc wirless sensor networks. [PDF]

, 2003
This paper considers the design of wireless sensor networks in which a set of smart battery-powered sensor nodes cooperatively form an ad hoc communications network for monitoring and control applications. The paper examines ways of extending the life of
Marshall, I. W., Blow, K. J., Hoding, D. J., Gao, Q.   +3 more
core   +3 more sources

Infrastructured ad hoc networks

Proceedings. International Conference on Parallel Processing Workshop, 2003
In traditional ad hoc networks, all nodes are considered equal and take equal part in the routing and forwarding of packets. We believe that this may not always be desirable. Rather, some nodes may be equipped with virtually unlimited power supplies, while others have to rely on battery power Thus, we propose the creation of "infrastructured" ad hoc ...
Lindgren, Anders, Schelén, Olov
openaire   +3 more sources

Communication issues in Large Scale Wireless Ad hoc Networks [PDF]

, 2005
Ad-hoc networks are networks that are formed automatically without any pre-existing infrastructure. These networks may consist of various types of mobile devices . such as PDAs, laptops, cell phones and other mobile computing devices.
Peart, Amanda, Owen, Gareth, Kasassbeh, M., Paraskelidis, Athanasios, Al-Kasassbeh, M., Al-Kasassbeh, Mouhammd, Adda, Mo   +6 more
core  

Realtime multiprocessor for mobile ad hoc networks [PDF]

, 2008
Jungeblut T, Grünewald M, Porrmann M, Rückert U. Realtime multiprocessor for mobile ad hoc networks. Advances in Radio Science. 2008;6:239-243.This paper introduces a real-time Multiprocessor System-On-Chip (MPSoC) for low power wireless applications ...
U. Rückert, T. Jungeblut, Jungeblut, Thorsten ; https://orcid.org/, Porrmann, Mario ; https://orcid.org/, Grünewald, Matthias, Rückert, Ulrich, M. Grünewald, M. Porrmann, Rückert, U., Grünewald, M., Jungeblut, Thorsten, Porrmann, M.   +11 more
core   +2 more sources

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Opinion Impact Models and Opinion Consensus Methods in Ad Hoc Tactical Social Networks

Discrete Dynamics in Nature and Society, 2013
Ad hoc social networks are special social networks, such as ad hoc tactical social networks, ad hoc firefighter social networks, and ad hoc vehicular social networks.
Demin Li, Jie Zhou, Jingjuan Zhu, Jiacun Wang   +3 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source