Results 61 to 70 of about 1,442,598 (260)

Renaissance-ada: Tools for analysis and transformation of ada code

open access: yes, 2022
In a constantly changing world, developers need to analyze and transform their code to keep it up-to-date and valuable. Currently, analysis and transformation is a time-consuming and largely manual activity.
Laar, P. van de, Mooij, A.J.
core  

Temporal‐Targeted Accelerated 40 Hz tACS Enhances Cognitive Function and Network Integration in Alzheimer's Disease: A Randomized Clinical Trial

open access: yesAdvanced Science, EarlyView.
Bilateral temporal accelerated 40‐Hz tACS improves cognitive function in patients with Alzheimer's disease. Resting‐state fNIRS identifies treatment‐related increases in frontotemporoparietal functional connectivity, which are associated with cognitive improvement. ABSTRACT The temporal lobes are key hubs for memory and cognition.
Rong Guo   +10 more
wiley   +1 more source

Antibodies with specificity to glycan motifs that decorate OMV cargo proteins

open access: yesmSphere
Porphyromonas gingivalis is a major etiological agent of periodontal disease, and infections with this bacterium are associated with systemic pathologies, including atherosclerosis, rheumatoid arthritis, and Alzheimer’s disease. P.
Hyun Young Kim   +3 more
doaj   +1 more source

Accounting Faculty Internships

open access: yesSAGE Open, 2013
Accounting professionals, business college accrediting bodies, and even accounting academics themselves acknowledge that there is a disconnect between academe and the rigors and requirements of the accounting profession. Among the suggestions proposed in
Jill Christopher   +2 more
doaj   +1 more source

Correspondence to Ada Peirce McCormick

open access: yes, 1910
Letters to Ada Peirce McCormick. The letters reflect the intimate friendship between Elizabeth Frances C. Clark (graduate of Woman's Medical College of Pennsylvania (WMCP) in 1909), Emma Elizabeth Musson (graduate of WMCP in 1883) and McCormick and daily
Clark, Elizabeth Frances C.   +2 more
core  

Immune Checkpoint Inhibitor as a Fifth Component of Lipid Nanoparticles Enables Lymph Node‐Targeting and Augments mRNA Vaccine Efficacy

open access: yesAdvanced Science, EarlyView.
Here, a PDL1 inhibitor is employed as a fifth component to modify lipid nanoparticles (LNPs). PDL1 inhibitor‐loaded LNPs show enhanced lymph node targeting, resulting in greater lymph node expansion, immune cell infiltration, and improved mRNA vaccine efficacy. This fifth component LNP could be a novel platform for mRNA vaccines.
Minki Ha   +5 more
wiley   +1 more source

Targeted elimination of Fusobacterium nucleatum alleviates periodontitis

open access: yesJournal of Oral Microbiology
Background Fusobacterium nucleatum, a pathobiont in periodontal disease, contributes to alveolar bone destruction. We assessed the efficacy of a new targeted antimicrobial, FP-100, in eradicating F.
Nil Yakar   +7 more
doaj   +1 more source

Correspondence to Ada Peirce McCormick

open access: yes, 1912
Letters to Ada Peirce McCormick. The letters reflect the intimate friendship between Elizabeth Frances C. Clark (graduate of Woman's Medical College of Pennsylvania (WMCP) in 1909), Emma Elizabeth Musson (graduate of WMCP in 1883) and McCormick and daily
Clark, Elizabeth Frances C.   +1 more
core  

Self‐Driving Laboratory Optimizes the Lower Critical Solution Temperature of Thermoresponsive Polymers

open access: yesAdvanced Intelligent Discovery, EarlyView.
A low‐cost, self‐driving laboratory is developed to democratize autonomous materials discovery. Using this "frugal twin" hardware architecture with Bayesian optimization, the platform rapidly converges to target lower critical solution temperature (LCST) values while self‐correcting from off‐target experiments, demonstrating an accessible route to data‐
Guoyue Xu, Renzheng Zhang, Tengfei Luo
wiley   +1 more source

Adenylation Domain Engineering Enables Biosynthesis of an Improved Polymyxin Antibiotic

open access: yesAngewandte Chemie, EarlyView.
To enable incorporation of l‐2‐aminodecanoic acid into polymyxin by fermentation, a single Trp‐to‐Ala substitution is rationally introduced into the adenylation‐domain residue of its nonribosomal peptide synthetase (NRPS) and efficiently switches substrate selectivity. The engineered strain produces biologically active Ada‐polymyxin, demonstrating that
Maximilian Müll   +7 more
wiley   +2 more sources

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