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The oral microbiome – an update for oral healthcare professionals [PDF]

British Dental Journal, 2016
For millions of years, our resident microbes have coevolved and coexisted with us in a mostly harmonious symbiotic relationship. We are not distinct entities from our microbiome, but together we form a 'superorganism' or holobiont, with the microbiome ...
M. Kilian, I. Chapple, M. Hannig, P. Marsh, V. Meuric, A. Pedersen, M. Tonetti, W. Wade, E. Zaura   +8 more
semanticscholar   +16 more sources

The Human Oral Microbiome [PDF]

Journal of Bacteriology, 2010
ABSTRACT The human oral cavity contains a number of different habitats, including the teeth, gingival sulcus, tongue, cheeks, hard and soft palates, and tonsils, which are colonized by bacteria. The oral microbiome is comprised of over 600 prevalent taxa at the species level, with distinct subsets predominating at
Floyd E. Dewhirst, Tuste Chen, Jacques Izard, Bruce J Paster, Anne C R Tanner, Wen-Han Yu, Abirami Lakshmanan, W. G. Wade   +7 more
semanticscholar   +4 more sources

Oral microbiome: Unveiling the fundamentals

Journal of Oral and Maxillofacial Pathology, 2019
The oral cavity has the second largest and diverse microbiota after the gut harboring over 700 species of bacteria. It nurtures numerous microorganisms which include bacteria, fungi, viruses and protozoa.
P. Deo, R. Deshmukh
semanticscholar   +3 more sources

Oral Microbiome and Alzheimer’s Disease

Microorganisms, 2023
The accumulation of amyloid-beta plaques in the brain is a central pathological feature of Alzheimer’s disease. It is believed that amyloid responses may be a result of the host immune response to pathogens in both the central nervous system and ...
Jason Wan, Hongkuan Fan
semanticscholar   +4 more sources

Impact of breastfeeding and other early-life factors on the development of the oral microbiome

Frontiers in Microbiology, 2023
The oral cavity is home to the second most diverse microbiome in the human body. This community contributes to both oral and systemic health. Acquisition and development of the oral microbiome is a dynamic process that occurs over early life; however ...
Roaa A. Arishi, Roaa A. Arishi, Ching T. Lai, Donna T. Geddes, Lisa F. Stinson   +4 more
doaj   +2 more sources

High iron-mediated increased oral fungal burden, oral-to-gut transmission, and changes to pathogenicity of Candida albicans in oropharyngeal candidiasis

Journal of Oral Microbiology, 2022
Background Iron affects the diversity of the oral microbial landscape. Laboratory-strain CAI4 of Candida albicans that causes oropharyngeal candidiasis (OPC) exhibits iron-induced changes to the cell wall, impacting phagocytosis (by macrophages) and ...
Aparna Tripathi, Anubhav Nahar, Rishabh Sharma, Trevor Kanaskie, Nezar Al-Hebshi, Sumant Puri   +5 more
doaj   +1 more source

Role of Cellular Metabolism during Candida-Host Interactions

Pathogens, 2022
Microscopic fungi are widely present in the environment and, more importantly, are also an essential part of the human healthy mycobiota. However, many species can become pathogenic under certain circumstances, with Candida spp. being the most clinically
Aize Pellon, Neelu Begum, Shervin Dokht Sadeghi Nasab, Azadeh Harzandi, Saeed Shoaie, David L. Moyes   +5 more
doaj   +1 more source

Transcription profiling reveals potential mechanisms of dysbiosis in the oral microbiome of rhesus macaques with chronic untreated SIV infection. [PDF]

, 2013
A majority of individuals infected with human immunodeficiency virus (HIV) have inadequate access to antiretroviral therapy and ultimately develop debilitating oral infections that often correlate with disease progression.
A Uehara, Aftab A. Ansari, Angeline T. Dang, AR Thurman, AT Dang, BA Dale, BL Shacklett, BP Gomes, Bruce J. Paster, C Beaurepaire, C Gervasoni, C Heise, Chin-Shang Li, Christina Murphy, D Preza, DA Reznik, DR Dixon, E Elinav, E Zaura, F Meurens, FE Dewhirst, G Diamond, G Diamond, G Xie, H Wang, H Yang, HT Rupniak, I Viard-Leveugle, J Benes, J Mitchell, JA Aas, JA Aas, JC Leao, JE Hull, JE Meyer, JM Garcia-Lechuz, JT Arotiba, L Feller, M Bando, M Bruewer, M Guadalupe, M Mittal, M Raffatellu, MD George, MD George, MD George, MH Shaw, Michael D. George, MP George, MT Pollanen, Niku Borujerdpur, P Regenhard, R Saini, RM Zakir, Ross Tarara, RS Veazey, S Chotai, S Gennaro, S Sugawara, Satya Dandekar, Sumathi Sankaran-Walters, Susan Ocon, T Chen, TG Shrihari, W Hartzell, Z Smit-McBride   +65 more
core   +13 more sources

Metabolic modelling of the human gut microbiome in type 2 diabetes patients in response to metformin treatment

npj Systems Biology and Applications, 2023
The human gut microbiome has been associated with several metabolic disorders including type 2 diabetes mellitus. Understanding metabolic changes in the gut microbiome is important to elucidate the role of gut bacteria in regulating host metabolism. Here,
Bouchra Ezzamouri, Dorines Rosario, Gholamreza Bidkhori, Sunjae Lee, Mathias Uhlen, Saeed Shoaie   +5 more
doaj   +1 more source

Professionalism in dentistry: deconstructing common terminology

BDJ Open, 2022
Background There is a social expectation that dentists demonstrate professionalism. Although the General Dental Council puts it at the heart of their regulatory agenda, there is not yet consensus on the meaning and implications of the term.
Andrew Trathen, Sasha Scambler, Jennifer E. Gallagher   +2 more
doaj   +1 more source