Results 21 to 30 of about 4,367 (214)

Needs-led human resource planning for Sierra Leone in support of oral health

open access: yesHuman Resources for Health, 2021
Background In Sierra Leone (SL), a low-income country in West Africa, dental care is very limited, largely private, and with services focused in the capital Freetown. There is no formal dental education.
Swapnil Gajendra Ghotane   +5 more
doaj   +1 more source

Molecular and cellular insight into Escherichia coli SslE and its role during biofilm maturation

open access: yesnpj Biofilms and Microbiomes, 2022
Escherichia coli is a Gram-negative bacterium that colonises the human intestine and virulent strains can cause severe diarrhoeal and extraintestinal diseases. The protein SslE is secreted by a range of pathogenic and commensal E. coli strains.
Paula M. Corsini   +19 more
doaj   +1 more source

Altered oral microbiome in Sudanese Toombak smokeless tobacco users carries a newly emerging risk of squamous cell carcinoma development and progression

open access: yesScientific Reports, 2023
There are an estimated 6–10 million smokeless tobacco (Toombak) users in Sudan, the majority being males. Toombak is known to be a carcinogenic product that is likely to modify the oral microbiome spatiality into a high-risk potential for the development
Amel Sami   +5 more
doaj   +1 more source

Soluble Dietary Fiber, One of the Most Important Nutrients for the Gut Microbiota

open access: yesMolecules, 2021
Dietary fiber is a widely recognized nutrient for human health. Previous studies proved that dietary fiber has significant implications for gastrointestinal health by regulating the gut microbiota.
Zhi-Wei Guan, En-Ze Yu, Qiang Feng
doaj   +1 more source

Candidalysin Is a Potent Trigger of Alarmin and Antimicrobial Peptide Release in Epithelial Cells

open access: yesCells, 2020
Host released alarmins and antimicrobial peptides (AMPs) are highly effective as antifungal agents and inducers. Whilst some are expressed constitutively at mucosal tissues, the primary site of many infections, others are elicited in response to ...
Jemima Ho   +5 more
doaj   +1 more source

A 16S rRNA Gene and Draft Genome Database for the Murine Oral Bacterial Community

open access: yesmSystems, 2021
A curated murine oral microbiome database to be used as a reference for mouse-based studies has been constructed using a combination of bacterial culture, 16S rRNA gene amplicon, and whole-genome sequencing.
Susan Joseph   +8 more
doaj   +1 more source

Oral Microbiome and Alzheimer’s Disease

open access: yesMicroorganisms, 2023
The accumulation of amyloid-beta plaques in the brain is a central pathological feature of Alzheimer’s disease. It is believed that amyloid responses may be a result of the host immune response to pathogens in both the central nervous system and peripheral systems. Oral microbial dysbiosis is a chronic condition affecting more than 50% of older adults.
Jason Wan, Hongkuan Fan
openaire   +3 more sources

EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway

open access: yesVirulence
Candida albicans is a fungal pathobiont colonizing mucosal surfaces of the human body, including the oral cavity. Under certain predisposing conditions, C.
Ruth E. Dickenson   +6 more
doaj   +1 more source

Candida albicans Interactions with Mucosal Surfaces during Health and Disease

open access: yesPathogens, 2019
Flexible adaptation to the host environment is a critical trait that underpins the success of numerous microbes. The polymorphic fungus Candida albicans has evolved to persist in the numerous challenging niches of the human body.
Spyridoula-Angeliki Nikou   +6 more
doaj   +1 more source

The dynamic communities of oral microbiome in neonates

open access: yesFrontiers in Microbiology, 2022
The oral microbiome, associated with both oral disease and systemic disease, is in dynamic status along the whole life, and many factors including maternal microbiomes could impact the oral microbiome. While fewer studies have been conducted to study the
Haiying Guo   +7 more
doaj   +1 more source

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