Comparison of bacterial culture and 16S rRNA community profiling by clonal analysis and pyrosequencing for the characterization of the dentine caries-associated microbiome [PDF]
, 2014 Culture-independent analyses have greatly expanded knowledge regarding the composition of complex bacterial communities including those associated with oral diseases.
Kathrin eSchulze-Schweifing +11 more
core +1 more source
Ras1-Independent High Iron-Mediated Hyphal Formation in Candida albicans
Journal of FungiC. albicans small GTPase Ras1 belonging to the cAMP-Protein Kinase A (PKA) signaling pathway is a well-established master regulator of hyphal development, taking its environmental cues from N-acetylglucosamine (GlcNAc) as a carbon source.
Deepak Parashar +2 more
doaj +1 more source
EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway
VirulenceCandida albicans is a fungal pathobiont colonizing mucosal surfaces of the human body, including the oral cavity. Under certain predisposing conditions, C.
Ruth E. Dickenson +6 more
doaj +1 more source
A 16S rRNA Gene and Draft Genome Database for the Murine Oral Bacterial Community
mSystems, 2021 A curated murine oral microbiome database to be used as a reference for mouse-based studies has been constructed using a combination of bacterial culture, 16S rRNA gene amplicon, and whole-genome sequencing.
Susan Joseph +8 more
doaj +1 more source
Role of Human Oral Microbiome in Diseases [PDF]
The human oral microbiome represents a diverse and intricate ecosystem comprising bacteria, fungi, viruses, and protozoa. It plays a vital role in numerous physiological processes, ranging from digestion to immunity.
Vijay Kumar Sinhal +6 more
core +1 more source
Candida albicans Interactions with Mucosal Surfaces during Health and Disease
Pathogens, 2019 Flexible adaptation to the host environment is a critical trait that underpins the success of numerous microbes. The polymorphic fungus Candida albicans has evolved to persist in the numerous challenging niches of the human body.
Spyridoula-Angeliki Nikou +6 more
doaj +1 more source
Candidalysin Is a Potent Trigger of Alarmin and Antimicrobial Peptide Release in Epithelial Cells
Cells, 2020 Host released alarmins and antimicrobial peptides (AMPs) are highly effective as antifungal agents and inducers. Whilst some are expressed constitutively at mucosal tissues, the primary site of many infections, others are elicited in response to ...
Jemima Ho +5 more
doaj +1 more source
iScience, 2022 Summary: The human gut microbiome has been associated with metabolic disorders including obesity, type 2 diabetes, and atherosclerosis. Understanding the contribution of microbiome metabolic changes is important for elucidating the role of gut bacteria ...
Ceri Proffitt +7 more
doaj +1 more source
APC Microbiome Ireland - 20 years of impact [PDF]
, 2023 In the 20 years since our foundation, APC Microbiome Ireland (APC) has had a profound and pioneering impact on the world of microbiome research. And our focus on such major societal challenges as chronic and infectious disease, anti-microbial resistance ...
Hogan, David
core
The dynamic communities of oral microbiome in neonates
Frontiers in Microbiology, 2022 The oral microbiome, associated with both oral disease and systemic disease, is in dynamic status along the whole life, and many factors including maternal microbiomes could impact the oral microbiome. While fewer studies have been conducted to study the
Haiying Guo +7 more
doaj +1 more source