Results 41 to 50 of about 4,367 (214)

Assessing the Effect of Smokeless Tobacco Consumption on Oral Microbiome in Healthy and Oral Cancer Patients

Frontiers in Cellular and Infection Microbiology, 2022
Oral cancer is a globally widespread cancer that features among the three most prevalent cancers in India. The risk of oral cancer is elevated by factors such as tobacco consumption, betel-quid chewing, excessive alcohol consumption, unhygienic oral ...
Rituja Saxena, Vishnu Prasoodanan P K, Sonia Vidushi Gupta, Sudheer Gupta, Prashant Waiker, Atul Samaiya, Ashok K. Sharma, Ashok K. Sharma, Vineet K. Sharma   +8 more
doaj   +1 more source

The sampling strategy of oral microbiome

iMeta, 2022
AbstractThere are multiple habitats in the oral cavity with bacteria, fungi, viruses, and protozoa residing in, which together constitute the oral micro‐ecosystem. These microflorae in the oral cavity primarily include saliva, supragingival dental plaque, subgingival dental plaque, submucosal plaque around implants, plaque in root canals, and plaque on
Hongye Lu, Peihui Zou, Yifei Zhang, Qian Zhang, Zhibin Chen, Feng Chen   +5 more
openaire   +3 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Candida albicans-induced ubiquitination of EGFR reveals novel host–fungal interaction pathways

mBio
Candida albicans causes severe mucosal and systemic infections, with hypha formation playing a key role in its virulence. Hyphal invasion via endocytosis is mediated predominantly through interactions between Als3p and the epidermal growth factor ...
Léa Lortal, James S. Griffiths, Emily L. Priest, Alexander Kempf, Olivia K. A. Paulin, Nicole O. Ponde, Antzela Tsavou, Don N. Wickramasinghe, Andrew Donkin, Claire M. Lyon, Olivia W. Hepworth, Jonathan P. Richardson, Julian R. Naglik   +12 more
doaj   +1 more source

Future Prospective of Oral Microbiome Research

Applied Sciences, 2021
Oral microbiome has complex structure. It consisted of more than 700 species of bacteria. These bacteria contains pathogens for human health. In contrast, some beneficial bacteria were included. Perspective of oral microbiome is not still elucidated.
Yoshiaki Nomura, Ayako Okada, Nobuhiro Hanada   +2 more
doaj   +1 more source

Human Gut Bacteria and Lipidic Nanoparticles: Particle Composition Predicts Structural Transformation and Bacterial Biocompatibility

Advanced Functional Materials, EarlyView.
Lipidic nanoparticles (LNPs) were incubated with 21 gut bacteria frequently associated with the human microbiome. SAXS revealed that ∼75% of tested species induced structural transformations in monoolein LNPs, whereas phytantriol and phospholipid formulations remained unaffected.
Jonathan Caukwell, Emily L. Gulliver, Livia Salvati Manni, Frithjof Herb, Caitlin Welsh, Samuel C. Forster, Andrew J. Clulow, Wye‐Khay Fong   +7 more
wiley   +1 more source

Suprathreshold non-volatile flavour perception is associated with multiple species rather than any single species via bacterial metabolism

Journal of Oral Microbiology
Background The microbiome is the characteristic microbial community inhabiting a well-defined habitat with distinct physicochemical properties. During eating, food is masticated and mixed with saliva to form a bolus; non-volatile flavour molecules are ...
Shuyuan Zhang, Saeed Shoaie, Guy H. Carpenter   +2 more
doaj   +1 more source

Uncultured Members of the Oral Microbiome

Journal of the California Dental Association, 2016
Around one-third of oral bacteria cannot be cultured using conventional methods. Some bacteria have specific requirements for nutrients while others may be inhibited by substances in the culture media or produced by other bacteria. Oral bacteria have evolved as part of multispecies biofilms, and many thus require interaction with other bacterial ...
Wade, W, Thompson, H, Rybalka, A, Vartoukian, S   +3 more
openaire   +2 more sources

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source