Candidalysin Is a Potent Trigger of Alarmin and Antimicrobial Peptide Release in Epithelial Cells
Cells, 2020 Host released alarmins and antimicrobial peptides (AMPs) are highly effective as antifungal agents and inducers. Whilst some are expressed constitutively at mucosal tissues, the primary site of many infections, others are elicited in response to ...
Jemima Ho +5 more
doaj +1 more source
The dynamic communities of oral microbiome in neonates
Frontiers in Microbiology, 2022 The oral microbiome, associated with both oral disease and systemic disease, is in dynamic status along the whole life, and many factors including maternal microbiomes could impact the oral microbiome. While fewer studies have been conducted to study the
Haiying Guo +7 more
doaj +1 more source
Scientific Reports, 2023 The exploration of oral microbiome has been increasing due to its relatedness with various systemic diseases, but standardization of saliva sampling for microbiome analysis has not been established, contributing to the lack of data comparability.
Eun-Ok Bang +8 more
semanticscholar +1 more source
Candida albicans Interactions with Mucosal Surfaces during Health and Disease
Pathogens, 2019 Flexible adaptation to the host environment is a critical trait that underpins the success of numerous microbes. The polymorphic fungus Candida albicans has evolved to persist in the numerous challenging niches of the human body.
Spyridoula-Angeliki Nikou +6 more
doaj +1 more source
Oral Microbiome: A Review of Its Impact on Oral and Systemic Health
MicroorganismsPurpose of review: This review investigates the oral microbiome’s composition, functions, influencing factors, connections to oral and systemic diseases, and personalized oral care strategies.
J. Rajasekaran +6 more
semanticscholar +1 more source
The oral microbiome, pancreatic cancer and human diversity in the age of precision medicine
Microbiome, 2022 Pancreatic cancer is a deadly disease with limited diagnostic and treatment options. Not all populations are affected equally, as disparities exist in pancreatic cancer prevalence, treatment and outcomes.
K. Herremans +6 more
semanticscholar +1 more source
Polymicrobial oral biofilm models: simplifying the complex [PDF]
, 2019 Over the past century, numerous studies have used oral biofilm models to investigate growth kinetics, biofilm formation, structure and composition, antimicrobial susceptibility and host–pathogen interactions.
Appelbaum +29 more
core +3 more sources
Enhanced Characterization of Drug Metabolism and the Influence of the Intestinal Microbiome: A Pharmacokinetic, Microbiome, and Untargeted Metabolomics Study. [PDF]
, 2020 Determining factors that contribute to interindividual and intra-individual variability in pharmacokinetics (PKs) and drug metabolism is essential for the optimal use of drugs in humans.
Alhaja, Maher +8 more
core +1 more source
EGR1 regulates oral epithelial cell responses to Candida albicans via the EGFR- ERK1/2 pathway
VirulenceCandida albicans is a fungal pathobiont colonizing mucosal surfaces of the human body, including the oral cavity. Under certain predisposing conditions, C.
Ruth E. Dickenson +6 more
doaj +1 more source
Analysis of the Effects of Dietary Pattern on the Oral Microbiome of Elite Endurance Athletes [PDF]
, 2019 Although the oral microbiota is known to play a crucial role in human health, there are few studies of diet x oral microbiota interactions, and none in elite athletes who may manipulate their intakes of macronutrients to achieve different metabolic ...
Burke, Louise M +8 more
core +3 more sources