Results 61 to 70 of about 1,597,894 (263)

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Nitrate supplementation affects taste by changing the oral metabolome and microbiome

npj Biofilms and Microbiomes
Nitrate, an inorganic anion found in various foods is also present in saliva and has emerged as a potential prebiotic for the oral microbiome. Salivary glands concentrate nitrate from the bloodstream and release it into the oral cavity via the anion ...
Shuyuan Zhang, Frederick Clasen, Haizhuang Cai, Thuy Do, Saeed Shoaie, Guy H. Carpenter   +5 more
doaj   +1 more source

Organic Materials of Tomorrow: Horizons of Artificial Intelligence

Advanced Materials, EarlyView.
This review examines machine learning techniques accelerating the discovery of organic semiconductors by linking molecular structure to properties. Key methods include graph neural networks, generative models, and active learning. Applications to organic photovoltaics demonstrate practical impact.
Harold Mena, J. Terence Blaskovits, Kun‐Han Lin, Denis Andrienko   +3 more
wiley   +1 more source

L-proline supplementation affects non-volatile flavour perception through oral microbiome metabolic pathways

npj Science of Food
L-proline is a non-essential amino acid that can be metabolised by the oral microbiome. This study hypothesised that L-proline could influence the microbiome and that shifts in the microbiome could subsequently affect non-volatile flavour perception.
Shuyuan Zhang, Saeed Shoaie, Guy H. Carpenter   +2 more
doaj   +1 more source

Suprathreshold non-volatile flavour perception is associated with multiple species rather than any single species via bacterial metabolism

Journal of Oral Microbiology
Background The microbiome is the characteristic microbial community inhabiting a well-defined habitat with distinct physicochemical properties. During eating, food is masticated and mixed with saliva to form a bolus; non-volatile flavour molecules are ...
Shuyuan Zhang, Saeed Shoaie, Guy H. Carpenter   +2 more
doaj   +1 more source

Oral mucosal injury in hematopoietic stem cell recipients:Emphasis on inflammation and the oral microbiome [PDF]

, 2022
The aim of this thesis was to describe oral complications associated with hematopoietic stem cell transplantation (HSCT) and to investigate the contribution of oral microorganisms in the pathogenesis of oral mucositis, a debilitating complication in HSCT
Haverman, T.M.
core  

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Regulatory and metabolic control of microbial biosynthetic gene clusters

Communications Biology
Microbial biosynthetic gene clusters (BGCs) encode diverse bioactive molecules but remain mostly silent under lab conditions, reflecting a balance between regulatory control and the metabolic cost of secondary metabolite production.
Idris Matine, Frederick Clasen, Fernando Garcia Guevara, Miao Guo, Saeed Shoaie   +4 more
doaj   +1 more source

Using next-generation sequencing to detect oral microbiome change following periodontal interventions: A systematic review

, 2021
Objectives This systematic review was to evaluate the change of oral microbiome based on next-generation sequencing (NGS)-metagenomic analysis following periodontal interventions among systematically healthy subjects.
Mei, ML, Dai, R, Lo, ECM, Qi, Y, McGrath, C, Zhang, Y   +5 more
core   +1 more source

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source