Results 121 to 130 of about 434,212 (312)

Shade adaptation of the Hawaiian tree-fern (Cibotium glaucum (Sm.) H. & A.) [PDF]

, 1974
Reports were scanned in black and white at a resolution of 600 dots per inch and were converted to text using Adobe Paper Capture Plug-inShade adaptation of both gametophytes and sporophytes of a Hawaiian tree-fern, (Cibotium glaucum (Sm.) H.
Friend, D.J.C.
core  

Adaptation and coevolution across environments [PDF]

, 2017
Epidemics are engines for host-parasite coevolution, where parasite adaptation to hosts drives reciprocal adaptation in host populations. A key challenge is to understand whether parasite adaptation and any underlying evolution and coevolution is ...
Auld, Stuart, Auld, Stuart K.J.R., Stuart K. J. R. Auld, June Brand, Brand, June   +4 more
core   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Balancing expenditures on mitigation of and adaptation to climate change : an exploration of Issues relevant to developing countries [PDF]

Although climate policies have been so far mostly focused on mitigation, adaptation to climate change is a growing concern in developed and developing countries. This paper discusses how adaptation fits into the global climate strategy, at the global and
Shalizi, Zmarak, Lecocq, Franck
core  

Habitat adaptation rather than genetic distance correlates with female preference in fire salamanders (Salamandra salamandra)

, 2009
Caspers B, Junge C, Weitere M, Steinfartz S. Habitat adaptation rather than genetic distance correlates with female preference in fire salamanders (Salamandra salamandra). Frontiers in Zoology. 2009;6(1):13.Background: Although some mechanisms of habitat
Steinfartz, Sebastian, Junge Claudia, Caspers Barbara A, Junge, C., Sebastian Steinfartz, Claudia Junge, Caspers, Barbara ; https://orcid.org/, Steinfartz, S., Weitere, Markus, Barbara A Caspers, Caspers, B.A., Weitere, M., Caspers, Barbara A, Weitere Markus, Markus Weitere, Junge, Claudia, Steinfartz Sebastian   +16 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Viral myocarditis in combination with genetic cardiomyopathy as a cause of sudden death. An autopsy series

BMC Cardiovascular Disorders
Sudden cardiac death (SCD) is a major public health issue worldwide. In the young (
Domitille Callon, Pierre Joanne, Laurent Andreoletti, Onnik Agbulut, Philippe Chevalier, Paul Fornès   +5 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

‘A Movie about Flowers’? Notes on the Ecological Turn in Adaptation Studies

This article takes up and responds to the recent ecological turn in adaptation studies, exploring the discipline’s widespread interest in the overlap between the notion of adaptation in evolutionary biology and the notion of adaptation in literature ...
Elliott, Tomas
core   +1 more source