Results 111 to 120 of about 434,212 (312)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Are there social limits to adaptation to climate change?
, 2010 While there is a recognised need to adapt to changing climatic conditions, there is an emerging discourse of limits to such adaptation. Limits are traditionally analysed as a set of immutable thresholds in biological, economic or technological parameters.
alexandre.magnan
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α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
When rapid adaptation paradigm is not too rapid: Evidence of face-sensitive N170 adaptation effects
, 2015 Recent findings have demonstrated that N170 adaptation effects evoked by face adaptors are general to face and non-face tests, implicating adaptor-locked interferences in the rapid adaptation paradigm.
Feng, Chunliang +4 more
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FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
, 2017 A central feature of Darwin’s theory of natural selection is that it explains the purpose of biological adaptation. Here, I: emphasise the scientific importance of understanding what adaptations are for, in terms of facilitating the derivation of ...
Andy Gardner, Gardner, Andy
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Hybrid Adaptive Fuzzy Control Based on the Biological Adaptation Strategies
Journal of Networks, 2013 For a class of uncertain nonlinear systems, this paper presents a method based on biological adaptation strategies of hybrid adaptive fuzzy control method. The method in the controller design, the ecological niche theory function as a consequent of the fuzzy rule fuzzy system, is established based on the biological adaptation of the adaptive controller.
Tong Zhao, Bingbing Qian, Yimin Li
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Co-evolution and networks adaptation. [PDF]
What is the role of co-evolution in the adaptation of a population of firms to a hostile environment ? To answer this question, we revisit network sociology starting from Kauffman s biological computer model.
Cartier, Manuel, Colovic, Ana
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