Results 71 to 80 of about 1,569,433 (340)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Review of moxifloxacin hydrochloride ophthalmic solution in the treatment of bacterial eye infections

Clinical Ophthalmology, 2008
Darlene MillerAbrams Ocular Microbiology Laboratory, Bascom Palmer Eye Institute, Anne Bates Leach Eye Hospital, Miller School of Medicine-University of Miami, FL, USAAbstract: Moxifloxacin hydrochloride ophthalmic solution 0.5% (Vigamox®) is the
Darlene Miller
doaj  

Histological Characterization of Ocular and Adnexal Tissues in Dogs (Canis familiaris) and Wolves (Canis lupus)

Anatomia
Background/Objectives: This study explores the ocular anatomy and glandular components of domestic dogs compared to their ancestor, the wolf, with the aim of identifying evolutionary changes due to domestication and their implications for ocular ...
Abel Diz López, Mateo V. Torres, Fabio Martínez Gómez, Silvia Alejandra Fraga Abelleira, Ana López-Beceiro, Luis Fidalgo, Pablo Sanchez-Quinteiro, Irene Ortiz-Leal   +7 more
doaj   +1 more source

Visuomotor Adaptation Brain Changes During a Spaceflight Analog With Elevated Carbon Dioxide (CO2): A Pilot Study

Frontiers in Neural Circuits, 2021
Astronauts on board the International Space Station (ISS) must adapt to several environmental challenges including microgravity, elevated carbon dioxide (CO2), and isolation while performing highly controlled movements with complex equipment.
Ana Paula Salazar, Kathleen E. Hupfeld, Jessica K. Lee, Lauren A. Banker, Grant D. Tays, Nichole E. Beltran, Igor S. Kofman, Yiri E. De Dios, Edwin Mulder, Jacob J. Bloomberg, Ajitkumar P. Mulavara, Rachael D. Seidler, Rachael D. Seidler   +12 more
doaj   +1 more source

Pilot Study of a New Rehabilitation Tool: Improved Unilateral Short-term Adaptation of the Human Angular Vestibulo-ocular Reflex

Otology and Neurotology, 2014
Hypothesis Unilateral vestibulo-ocular reflex (VOR) short-term adaptation training causes some increase toward the nonadapting side (∼30% of increase on adapting side). We conducted a pilot study to determine if the increase could be reduced by providing
A. Migliaccio, M. Schubert
semanticscholar   +1 more source

What visual information is used for stereoscopic depth displacement discrimination? [PDF]

, 2012
There are two ways to detect a displacement in stereoscopic depth, namely by monitoring the change in disparity over time (CDOT) or by monitoring the inter-ocular velocity difference (IOVD).
Harris, Julie, Nefs, Harold
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

A comprehensive review of resistome profiles in ocular pathogens: Insights into Pseudomonas aeruginosa and emerging resistance trends

Journal of Infection and Public Health
Eye infections are a significant area of microbial adaptation and therapeutic challenge, as antibiotic resistance threatens vision. In the last ten years, our knowledge of the ocular resistome has expanded through genomics and molecular epidemiology.
Raghav Krishnan Kulandaivelu, Aditi Roy, Soham Roy, J.S. Amith Velavan, Reddysai Amudala, Debraj Joel Das Adhikari, Karan S.V., Sudha Ramaiah, Anand Anbarasu   +8 more
doaj   +1 more source

Vision and Reading Difficulties Part 2: Optometric correlates of reading difficulties [PDF]

, 2009
In this second article of the series on vision and reading difficulties, the optometric factors (for example refractive error and orthoptic function) that may be associated with reading problems are discussed in detail.
Allen, Peter M, Evans, Bruce J W, Wilkins, Arnold   +2 more
core  

Spinocerebellar Ataxia Type 2 [PDF]

, 2012
1. Introduction: The autosomal dominant cerebellar ataxias (ADCA) are a clinically, pathologically and genetically heterogeneous group of neurodegenerative disorders caused by degeneration of cerebellum and its afferent and efferent connections.
Auburger, Georg, Freund, Hans-Joachim, Rodríguez-Labrada, Roberto, Velázquez-Pérez, Luis   +3 more
core   +1 more source