Results 61 to 70 of about 1,569,433 (340)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Regional and central hemodynamics in ischemic optic neuropathy

Journal of Ophthalmology, 2018
Background: As ocular vascular disorders are a major cause of visual loss and affect working-age individuals, they are of particular social importance. Purpose: To investigate visual functions and ocular hemodynamics in ischemic optic neuropathy (ION)
N.I. Khramenko, N.V. Konovalova, O.V. Guzun   +2 more
doaj   +1 more source

Thai version of the dry eye-related quality-of-life score questionnaire: preliminary assessment for psychometric properties

BMC Ophthalmology, 2021
Background This study aimed to develop a Thai version of the Dry Eye–Related Quality-of-Life Score (DEQS-Th) questionnaire and evaluate its validity, reliability, and feasibility among Thai participants.
Sasiwimon Tansanguan, Napaporn Tananuvat, Nahathai Wongpakaran, Tinakon Wongpakaran, Somsanguan Ausayakhun   +4 more
doaj   +1 more source

Visual Adaptation to Scattering in Myopes

Photonics, 2021
Myopes exhibit a larger capability of adaptation to defocus. Adaptation produces a boost in visual performance that can be characterized through different metrics.
José A. Villa-Carpes, Juan M. Bueno, Enrique J. Fernández   +2 more
doaj   +1 more source

Multiparameter vision testing apparatus [PDF]

, 1975
Compact vision testing apparatus is described for testing a large number of physiological characteristics of the eyes and visual system of a human subject.
Homkes, R. J., Hunt, S. R., Jr., Poteate, W. B., Sturgis, A. C.   +3 more
core   +1 more source

Keratoprostheses for corneal blindness: a review of contemporary devices [PDF]

, 2015
According to the World Health Organization, globally 4.9 million are blind due to corneal pathology. Corneal transplantation is successful and curative of the blindness for a majority of these cases. However, it is less successful in a number of diseases
Avadhanam, Venkata, Liu, Christopher, Smith, Helen   +2 more
core   +1 more source

A Multiple Stakeholder Multicriteria Decision Analysis in Diabetic Macular Edema Management: The MULTIDEX‑EMD Study [PDF]

, 2020
Background The clinical and economic management of retinal diseases has become more complex following the introduction of new intravitreal treatments. Multicriteria decision analysis (MCDA) offers the potential to overcome the challenges associated with ...
Casado, Miguel Ángel, Cervera, Enrique, de Andrés‑Nogales, Fernando, García Layana, Alfredo, Ignacio García, Emilio Francisco, Llorente, Iñaki, Martínez Olmos, José, Martínez Sesmero, José Manuel, Martínez, Mercedes, Mur, Carlos, Ortiz, Pere, Peralta, Gemma, Poveda, José Luis, Rodríguez Maqueda, Mariano, Ruiz Moreno, José María, Trillo, José Luis, Udaondo, Patricia, Zarranz Ventura, Javier, Zulueta, Jacinto, Álvarez, Eloísa   +19 more
core   +3 more sources

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

A Cerebellar Learning Model of Vestibulo-Ocular Reflex Adaptation in Wild-Type and Mutant Mice

Journal of Neuroscience, 2014
Mechanisms of cerebellar motor learning are still poorly understood. The standard Marr–Albus–Ito theory posits that learning involves plasticity at the parallel fiber to Purkinje cell synapses under control of the climbing fiber input, which provides an ...
C. Clopath, A. Badura, C. D. De Zeeuw, N. Brunel   +3 more
semanticscholar   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source