Advanced Science, EarlyView.NSUN2 and m5C decline in URSA villous tissues. Trophoblast Nsun2 ablation disrupts macrophage‐mediated maternal‐fetal tolerance and triggers embryo resorption. Mechanistically, NSUN2‐YBX1 axis stabilizes m5C‐modified TGFB1 mRNA to maintain TGF‐β1 secretion and M2 polarization, and restoring this signaling rescues maternal‐fetal immune tolerance to ...
Xiaoxiao Zhu +10 more
wiley +1 more source
Tumor Exposomics: A New Paradigm for Individualized Continuous Exposure Monitoring
Advanced Science, EarlyView.Tumor exposomics integrates continuous monitoring of environmental exposures, endogenous biological responses, and behavioral factors within a unified temporal framework. By combining multimodal sensing technologies with AI‐enabled causal modeling, this emerging paradigm reconstructs exposure‐damage trajectories and supports individualized dynamic risk
Kaicheng Shen +6 more
wiley +1 more source
Smoking and Health Investments: Impacts of Health Adaptation and Damage Reversibility [PDF]
In the present paper we examine how different sets of beliefs about the health effects of smoking would influence a rational smoker. By embedding the rational addiction theory in a Grossman model of health investment modified to take account of ...
Carbone, Jared +2 more
core
The Connection Between Personality and the Perception of Social Norms in the Adaptation to the Principles of Sustainable Development. [PDF]
Int J PsycholNagymzhanova K +4 more
europepmc +1 more source
A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation
Advanced Science, EarlyView.A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang +5 more
wiley +1 more source
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT To increase farmer adoption of green practices, the EU Common Agricultural Policy includes both mandatory (conditionality) and voluntary instruments (eco‐schemes–ECS– and more demanding, multi‐annual agri‐environment‐climate measures –AECM–). Building on the experiment of Barreiro‐Hurle et al.
L. Sanchez‐Mata +4 more
wiley +1 more source
Social Support and Mental Health Across a Public Health Crisis Lifecycle: A Three-Wave Repeated Cross-Sectional Study of Mediating Coping Mechanisms. [PDF]
Psychol Res Behav ManagXu S, Wang W, Cao K, Shi C.
europepmc +1 more source
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Growing demand for healthier beverages is driving innovation in the wine sector, with dealcoholized wine emerging as a promising alternative. However, little is known about the contextual conditions under which consumers would choose dealcoholized wine, particularly in countries with strong wine traditions. To fill this gap, this work examines
Giovanna Piracci +4 more
wiley +1 more source
Digitally Adapting LGBTQ-Affirmative Cognitive Behavioral Therapy for Chinese Men Who Have Sex With Men Living With HIV: User-Centered Design Approach. [PDF]
J Med Internet ResWu W +9 more
europepmc +1 more source
Behavioral Coping With Food Price Inflation: Patterns Among U.S. Households
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Recent food price inflation has placed substantial pressure on household budgets, food security, and mental well‐being. Using Household Pulse Survey data, we combine k‐modes clustering and Double Machine Learning to identify distinct household coping groups and examine differences in how households respond to rising food prices across groups ...
Yuxiang Zhang, Yizao Liu
wiley +1 more source