Targeting p38α in cancer: challenges, opportunities, and emerging strategies
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley +1 more source
Zaščitna cepljenja v otroški dobi
A. Wallgren; priredba/adaptation Hermina Andoljšek
doaj
Adapting Measures of Anxiety and Mood Disorders for Use with Autistic Adults: A Systematic Review. [PDF]
Wilkinson E +5 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dispanzerji in posvetovalnice za otroke v sr sloveniji
Marta Hočevar-Kuharič +1 more
doaj
Cultural congruence and educational equity: how ethnic minority teachers promote minority students' school adaptation and its underlying psychological mechanisms. [PDF]
Ouyang Z, Jing L, Li C, Tang J.
europepmc +1 more source
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Adapting a culturally grounded diabetes prevention program for Latino families in the Phoenix, Arizona metropolitan area - A mixed methods approach. [PDF]
Diaz M +6 more
europepmc +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Blindfolded hypogravity adaptation differentially affects motor and cognitive systems. [PDF]
Rock CG, Kim H, Dick JF, Chang YH.
europepmc +1 more source

