Results 151 to 160 of about 1,276,486 (299)

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Kako naj se medicinska sestra in bolnik obvarujeta razčlovečenja spričo vedno večjega napredka tehnike v medicini?

Obzornik zdravstvene nege, 1970
priredna/adaptation Anica Gradišek
doaj  

Strengthening Kenya's public health response to reproductive coercion and intimate partner violence in family planning clinics: applying the FRAME + IS approach. [PDF]

Front Reprod Health
Menzel J, Uysal J, Pearson E, Namwebya J, Gathitu M, Mwangangi A, Okumu C, Chirchir B, Liambila W, Odwe G, Serem E, Undie CC, Silverman J.   +12 more
europepmc   +1 more source

Uncertainty and climate change adaptation : a scoping study

, 2007
Suraje Dessai, J.P. van der Sluijs
openalex   +1 more source

Survival Strategies for Telecom Operators in the Age of OTT Disruption: A Business Model Analysis of Revenue Diversification and Market Adaptation

A H M Jafor -, Md. Easin Arafat, Mir Abrar Hossain, Md. Monirul Islam   +3 more
openalex   +2 more sources

REQUIREMENTS FOR FORMIC HYDROGENLYASE ADAPTATION IN NONPROLIFERATING SUSPENSIONS OF ESCHERICHIA COLI [PDF]

, 1952
Mariel Pinsky, J. L. Stokes
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Novosti - izkušnje - pobude

Obzornik zdravstvene nege, 1969
priredba/adaptation: M.J.; Silvija Dekleva
doaj  

Clinical nurse educators' role in supporting new nurses: qualitative insights into practice adaptation training in a tertiary hospital in South Korea. [PDF]

BMC Nurs
Ahn S, Jeong HW.
europepmc   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source