Results 41 to 50 of about 534,103 (285)

Retinal adaptation of Japanese common squid (Todarodes pacificus Steenstrup) to light changes [PDF]

, 1985
The response of retinae of the Japanese common squid (Todarodes pacificus Steenstrup) was recorded in relation to various light intensities. In the light-adapted eye of common squid, the black pigment ascends to the external limiting membrance of the ...
Hiroshi, Inada, Hiroya, Takahashi, Tsuneyoshi, Suzuki   +2 more
core  

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

A differential role for the posterior cerebellum in the adaptive control of convergence eye movements

Brain Stimulation, 2020
Introduction: The vergence oculomotor system possesses two robust adaptive mechanisms; a fast “dynamic” and a slow “tonic” system that are both vital for single, clear and comfortable binocular vision.
Ian M. Erkelens, William R. Bobier, Alicia C. Macmillan, Nicole L. Maione, Claudia Martin Calderon, Heidi Patterson, Benjamin Thompson   +6 more
doaj   +1 more source

Scaling of Horizontal and Vertical Fixational Eye Movements

, 2004
Eye movements during fixation of a stationary target prevent the adaptation of the photoreceptors to continuous illumination and inhibit fading of the image. These random, involuntary, small, movements are restricted at long time scales so as to keep the
A. Bunde, Ari Z. Zivotofsky, Avi Caspi, J. M. Hausdorff, Jin-Rong Liang, M. B. Clowes, R. Engbert, Ralf Engbert, Reinhold Kliegl, Shay Moshel, Shlomo Havlin, W. Bair   +11 more
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prosthodontic rehabilitation of patient with ocular defect using an alternative technique

Journal of Orofacial Sciences, 2012
An ocular prosthesis is a simulation of of a perfectly normal healthy eye and surrounding tissues. The primary purpose of an ocular prosthesis is to maintain the volume of eye socket and create the illusion of a healthy eye and surrounding tissue.
Laxman Singh Kaira, Nag Bhusan Mandal, S Swarajya Bharathi   +2 more
doaj   +1 more source

Beyond the Liver: Liver-Eye Communication in Clinical and Experimental Aspects

Frontiers in Molecular Biosciences, 2021
The communication between organs participates in the regulation of body homeostasis under physiological conditions and the progression and adaptation of diseases under pathological conditions.
Tian-Hao Yuan, Tian-Hao Yuan, Zhen-Sheng Yue, Zhen-Sheng Yue, Guo-Heng Zhang, Lin Wang, Guo-Rui Dou   +6 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Visual space constructed by saccade motor maps

Frontiers in Human Neuroscience, 2016
How visual space is represented in the brain is an open question in neuroscience. Embodiment theories propose that spatial perception is structured by neural motor maps.
Eckart Zimmermann, Markus Lappe
doaj   +1 more source