Genetic Variation in Human Gene Regulatory Factors Uncovers Regulatory Roles in Local Adaptation and Disease [PDF]
, 2019 Differences in gene regulation have been suggested to play essential roles in the evolution of phenotypic changes. Although DNA changes in cis-regulatory elements affect only the regulation of its corresponding gene, variations in gene regulatory factors
Nowick, Katja, Perdomo-Sabogal, Álvaro
core +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
FEBS Open Bio, EarlyView.A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Adaptation of social and non-social cues to direction in adults with autism spectrum disorder and neurotypical adults with autistic traits [PDF]
, 2017 Perceptual constancy strongly relies on adaptive gain control mechanisms, which shift perception as a function of recent sensory history. Here we examined the extent to which individual differences in magnitude of adaptation aftereffects for social and ...
Aylward, J +3 more
core
Perception, cognition, and action in hyperspaces: implications on brain plasticity, learning, and cognition [PDF]
, 2020 We live in a three-dimensional (3D) spatial world; however, our retinas receive a pair of 2D projections of the 3D environment. By using multiple cues, such as disparity, motion parallax, perspective, our brains can construct 3D representations of the ...
Ogmen, Haluk +2 more
core +1 more source
Cartographic adaptation through eye tracking and deep learning: Gaze-Aware Interactive Map System (GAIMS) [PDF]
, 2022 Merve Keskin +2 more
openalex +1 more source
FEBS Open Bio, EarlyView.Mitochondria‐associated membranes (MAMs) are contact sites between the endoplasmic reticulum and mitochondria that regulate calcium signaling, lipid metabolism, autophagy, and stress responses. This review outlines their molecular organization, roles in cellular homeostasis, and how dysfunction drives neurodegeneration, metabolic disease, cancer, and ...
Viet Bui +3 more
wiley +1 more source
Child eye health in Ethiopia: a mixed methods analysis of policy and commitment to action
BMJ Open, 2023 Background Child eye health is a serious public health issue in Ethiopia, where children under the age of 15 account for over half of the population.
Samson Tesfaye +4 more
doaj +1 more source
Human visual response to nuclear particle exposures [PDF]
, 1972 Experiments with accelerated helium ions were performed in an effort to localize the site of initial radiation interactions in the eye that lead to light flash observations by astronauts during spaceflight.
Budinger, T. F. +2 more
core +1 more source
Characteristics of Cerebral Palsy in the Midwestern US
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Cerebral palsy (CP) is the most common lifelong motor disability worldwide. Yet, data is limited on how CP manifests in the US. Our objective was to characterize and determine factors affecting functional outcomes in a large population of young people with CP in the Midwestern US.
Susie Kim +6 more
wiley +1 more source
Saccade Dynamics in the Acute and Recovery Phase of Abducens Nerve Palsy
Journal of Ophthalmic & Vision ResearchPurpose: To examine the natural adaptive course of ocular motor system in unilateral abducens nerve palsy while addressing the scarce literature on saccade dynamics and natural adaptation.
Elissavet Kemanetzoglou +4 more
doaj +1 more source