Results 71 to 80 of about 5,788,215 (257)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Global Goal on Adaptation - Science for Adaptation Policy Brief #6

open access: yes, 2022
The WASP Science-for-Adaptation Policy Brief on the Global Goal on Adaptation is the sixth issue in the series published by seven United Nations agencies that form the World Adaptation Science Programme (WASP): UN Environment Programme (UNEP), the World ...
Ebi, Kristie L.   +2 more
core  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Using Forests to Enhance Resilience to Climate Change : What Do We Know About How Forests Can Contribute to Adaptation?

open access: yes, 2012
The global dialogue surrounding the United Nations framework convention for climate change has focused on two strategies for addressing challenges associated with climate change: (1) mitigation (reducing the
World Bank
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Climate Change Adaptation Strategies for Australian Birds

open access: yes, 2013
In the first continental analysis of the effects of climate change on a faunal group, we identified that the climate space of 101 Australian terrestrial and inland water bird taxa is likely to be entirely gone by 2085, 16 marine taxa have breeding sites ...
Ehmke, Glenn   +10 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Assessing the determinants of rice farmers' adaptation strategies to climate change in Bangladesh

open access: yes, 2013
Purpose - This paper examines rice farmers' selection of adaptation strategies to cope with and offset the effects of climate change and the determinants of those selections in Rajshahi, a severely drought-prone district of Bangladesh.
Gow, Jeff   +2 more
core   +1 more source

Récit d’une adaptation : République Dominicaine [PDF]

open access: yes, 2021
En los últimos años, las comunidades vulnerables de las zonas rurales de la provincia de San Cristóbal, en la República Dominicana, se han enfrentado a impactos climáticos intensos y a una variabilidad de las precipitaciones que ponen en peligro los ...
Adaptation Fund
core  

Enhancing resilience to climate change: a comprehensive PRISMA review of agricultural and non-agricultural adaptation strategies for Ghana

open access: yesCogent Social Sciences
Farming in Ghana is highly vulnerable to climate change due to factors such as limited financial resources, inadequate land availability, lack of access to technology, and insufficient public infrastructure, including roads, weather forecasting systems ...
Silas Uwumborge Takal   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy